慢性肺源性心脏病合并呼吸衰竭的营养支持治疗

Nutritional supportive therapy for chronic pulmonary heart disease complicating with respiratory failure

目的观察合理使用营养支持疗法治疗慢性肺源性心脏病(肺心病)合并呼吸衰竭的疗效。方法慢性肺心病合并呼吸衰竭患者60倒,随机分成2组:对照组(n=30)采用病员标准饮食,营养支持组(n=30)在对照组基础上加用营养支持疗法。比较2组患者营养指标、免疫功能、血气分析指标、治疗效果及住院时间的差异。结果营养支持组前白蛋白、肌酐身高指数(cHI)及淋巴细胞总数(tLC)较对照组升高更为明显(P<0.05);营养支持组p(O2)升高和p(CO2)下降较对照组更为明显(P<0.05);营养支持组好转率90%(27/30),达到治疗好转的住院时间为(15.8±4.25)d;对照组患者治疗好转率77%(23/30),达到治疗好转的住院时间为(20.6±3.61)d;2组各自比较均有显著性差异(P<0.05)。结论合理的营养疗法在慢性肺心病急性加重并呼吸衰竭治疗中至关重要。

Objective It is to explore the curative effect of reasonable nutritional supportive therapy on chronic pulmonary heart disease complicating with respiratory failure. Methods Sixty patients with chronic pulmonary heart disease complicating with respiratory failure were selected and grouped into control group（ n = 30） treated with standard diet therapy and nutritional supportive therapy group （ n = 30） treated with the standard diet plus nutritional support. The nutritional supportive index, im- mune function, arterial blood gases, therapeutic effects and hospital stay time were compared between both groups. Results The level of prealbumin, CHI and TLC in nutritional supportive therapy group were increased more remarkably than that in con- trol group （ P 〈 0.05 ）. The level of p（ O2） was increased and the level of p（ CO2 ） was decreased more obviously in nutritional supportive therapy group than that in control group （P 〈 0.05）. The rate of respond well and the hospital stay time in nutrition- al supportive therapy group were 90% and （15.8± 4.25）days, and the rate and the time in control group were 77% and （20. 6 ± 3.61 ） days, compared with each other, the differences were significant（P 〈 0.05）. Conclusion Reasonable nutri- tional supportive therapy is of important significance for chronic pulmonary heart disease complicating with respiratory failure.