摘要
目的探讨经支气管动脉灌注化疗(bronchial artery infusion,BAI)联合CT引导下的放射性125I粒子植入术治疗周围型肺癌的疗效。方法采用经支气管动脉灌注化疗联合CT引导下的放射性125I粒子植入术治疗23例不愿接受手术治疗或不能耐受手术的周围型肺癌患者。结果 23例患者中CR 5例,PR 11例,SD 5例,PD 2例;中位生存期为296天;23例中有4例发生Ⅲ度骨髓抑制,2例发生Ⅱ度骨髓抑制,经治疗后缓解,无1例发生放射性肺炎。结论BAI联合125I粒子植入术是治疗周围型肺癌较为有效、安全的方法。
Objective To evaluate the efficacy of treating peripheral pulmonary carcinoma with bronchial artery infusion and Iodine-125 seed implantation.Methods 23 patients diagnosed as peripheral pulmonary carcinoma,who refused or can not tolerate surgical operation were treated with bronchial artery infusion and Iodine-125 seed implantation.Results The overall response rate was 69.6%,including CR 5 cases and PR 11 cases,SD 5 cases,PD 2 cases.MST were 296 days.There were 4 cases with Ⅲ degree arrest of bone marrow and 2 cases with II degree arrest of bone marrow,they all recoverd after therapy and none had radiation pneumonitis.Conclusion BAI combined with Iodine-125 seed implantation shows better clinical efficacy than chemotherapy through vein in treating the peripheral pulmonary carcinoma.It is a more effective and safe method to treat the peripheral pulmonary carcinoma.
出处
《实用癌症杂志》
2013年第1期51-52,61,共3页
The Practical Journal of Cancer
