摘要
目的探讨隆突性皮肤纤维肉瘤的临床病理特征。方法对25例隆突性皮肤纤维肉瘤的临床表现、组织形态学和免疫组化进行分析。结果全部病例根据临床表现、组织结构、细胞形态及免疫组化确诊。免疫组化示:vim-entin阳性率100%(25/25),CD34阳性率100%(25/25),Ki-67阳性率60%(15/25),SMA阳性率32%(8/25),actin阳性率40%(10/25),CD68、S-100、FⅧa及CK均阴性。结论隆突性皮肤纤维肉瘤容易误诊,需多做切片寻找典型结构和免疫组化进行确诊。
Objective To study the clinicopathological characteristics of dermatofibrosarcoma protuberans（DFSP）.Methods Clinical pathological characteristics and immunohistochemical findings were observed in 25 cases of dermatofibrosarcoma protuberans.Results All cases of dermatofibrosarcoma protuberans（DFSP） were diagnosed by clinical characteristics、histopathologic characteristics、cell form and immunohistochemistry.Immunohistochemiscal staining showed that the tumor cells were positive for vimentin（100%、25/25）,CD34（100%,25/25）,Ki-67（60%,15/25）,SMA（32%、8/25）,actin（40%、10/25）,while CD68、S-100、FⅧa and CK did not express.Conclusion DFSP is misdiagnosed easily.It is better for the diagnosis to find classical tissues structure and use immunohistochemistry.
出处
《实用癌症杂志》
2013年第1期70-72,共3页
The Practical Journal of Cancer
关键词
隆突性皮肤纤维肉瘤
临床病理
Dermatofibrosarcoma protuberans（DFSP）
Clinicopathologic
