有氧运动对焦虑大鼠血清甲状腺激素(TH)、多巴胺(DA)的水平影响研究

Analysis on Influence of Aerobic Exercise on Serum Contents of Thyroid Hormone(TH) and Dopamine(DA)in Anxious Rats

目的 :观察焦虑大鼠和有氧运动焦虑大鼠血清甲状腺激素(TH)、多巴胺(DA)的含量的变化。方法 :清洁级SD雄性大鼠60只随机分成3组,即:A组自然对照组(national control group)(n=20),B组基础对照组(Foundation control group)(n=20),C组有氧运动组(aerobic exercise group)(n=20)。用昼夜颠倒的方法制焦虑大鼠模型。将B组、C组40只大鼠白天置于黑暗密闭空间,晚上用灯管照明,共持续14 d。自然对照组和基础对照组:40只大鼠每天自由饮食。有氧运动组:让焦虑模型大鼠20只每周1、3、5进行持续1 h的动物跑台跑步训练,共持续6周。结果 :有氧运动组大鼠与基础对照组相比,大鼠血清甲状腺激素(TH)、多巴胺(DA)的含量明显低于基础对照组(P<0.01);有氧运动组大鼠与自然对照组相比,大鼠血清甲状腺激素(TH)、多巴胺(DA)的含量低于自然对照组(P<0.05);自然对照组与基础对照组比较:大鼠血清甲状腺激素(TH)、多巴胺(DA)的含量明显低于基础对照组(P<0.01)。结论 :适宜的有氧运动可以缓解大鼠的焦虑程度,降低焦虑大鼠血清甲状腺激素(TH)、多巴胺(DA)的水平,是一种有效地缓解焦虑的方法,值得广泛推广。

Ohjective： To observe the content changes in serum of thyroid hormone （ TH ）and dopamine （ DA ） of anxious rats and aerobic exercise anxious rats. Method ： 60 clean level SD male rats were randomly divided into 3 groups ： group A natural control group （ n=20 ）, group B foundation control group （ n=20 ）, group C aerobic exercise group （ n=20 ）. 40 rats in group B and C were in the darkness during the day and at night given light tube lighting, lasting for 14 days. In the nature and foundation control groups： 40 rats fed freely every day. Aerobic exercise group： rats were forced to do a training run for 1 hour on Monday, Wednesday and Friday in every week, lasting for six weeks. Results： Compared with controls, thyroid hormone （ TH ） and dopamine （ DA ） in serum of aerobic exercise rats were obviously lower than that in the foundation control group （ P〈0.01 ）. Compared with the nature control group, thyroid hormone （ TH ） and dopamine （ DA ） in aerobic exercise group rats were lower than that in the natural control group （ P〈0.05 ）. Compared with the foundation control group, thyroid hormone （ TH ） and dopamine （ DA ） were in aerobic exercise rats were obviously lower than that in the foundation control group （P〈0.01）. Conclusion： Appropriating aerobic exercise can ease the anxiety level in rats, reduce anxiety rats serum levels of thyroid hormone （ TH ） and dopamine （ DA ）, which is an effective method to ease anxiety and is worthy of popularizing widely.