摘要
目的 :观察焦虑大鼠和有氧运动焦虑大鼠血清甲状腺激素(TH)、多巴胺(DA)的含量的变化。方法 :清洁级SD雄性大鼠60只随机分成3组,即:A组自然对照组(national control group)(n=20),B组基础对照组(Foundation control group)(n=20),C组有氧运动组(aerobic exercise group)(n=20)。用昼夜颠倒的方法制焦虑大鼠模型。将B组、C组40只大鼠白天置于黑暗密闭空间,晚上用灯管照明,共持续14 d。自然对照组和基础对照组:40只大鼠每天自由饮食。有氧运动组:让焦虑模型大鼠20只每周1、3、5进行持续1 h的动物跑台跑步训练,共持续6周。结果 :有氧运动组大鼠与基础对照组相比,大鼠血清甲状腺激素(TH)、多巴胺(DA)的含量明显低于基础对照组(P<0.01);有氧运动组大鼠与自然对照组相比,大鼠血清甲状腺激素(TH)、多巴胺(DA)的含量低于自然对照组(P<0.05);自然对照组与基础对照组比较:大鼠血清甲状腺激素(TH)、多巴胺(DA)的含量明显低于基础对照组(P<0.01)。结论 :适宜的有氧运动可以缓解大鼠的焦虑程度,降低焦虑大鼠血清甲状腺激素(TH)、多巴胺(DA)的水平,是一种有效地缓解焦虑的方法,值得广泛推广。
Ohjective: To observe the content changes in serum of thyroid hormone ( TH )and dopamine ( DA ) of anxious rats and aerobic exercise anxious rats. Method : 60 clean level SD male rats were randomly divided into 3 groups : group A natural control group ( n=20 ), group B foundation control group ( n=20 ), group C aerobic exercise group ( n=20 ). 40 rats in group B and C were in the darkness during the day and at night given light tube lighting, lasting for 14 days. In the nature and foundation control groups: 40 rats fed freely every day. Aerobic exercise group: rats were forced to do a training run for 1 hour on Monday, Wednesday and Friday in every week, lasting for six weeks. Results: Compared with controls, thyroid hormone ( TH ) and dopamine ( DA ) in serum of aerobic exercise rats were obviously lower than that in the foundation control group ( P〈0.01 ). Compared with the nature control group, thyroid hormone ( TH ) and dopamine ( DA ) in aerobic exercise group rats were lower than that in the natural control group ( P〈0.05 ). Compared with the foundation control group, thyroid hormone ( TH ) and dopamine ( DA ) were in aerobic exercise rats were obviously lower than that in the foundation control group (P〈0.01). Conclusion: Appropriating aerobic exercise can ease the anxiety level in rats, reduce anxiety rats serum levels of thyroid hormone ( TH ) and dopamine ( DA ), which is an effective method to ease anxiety and is worthy of popularizing widely.
出处
《辽宁中医药大学学报》
CAS
2013年第2期102-104,共3页
Journal of Liaoning University of Traditional Chinese Medicine
基金
陕西省教育厅课题