马晓燕教授以毒论治紫癜性肾炎病因病机述要

Summary of Etiology and Pathogenesis of HSPN Treated by Professor Ma Xiaoyan Based on Toxin

以毒邪的角度对紫癜性肾炎的病因病机做以分析,其主要致病因素为"热毒、瘀毒、湿毒",热毒多见于早期,瘀毒贯穿病程始终,湿毒使病程缠绵,热毒、湿毒、瘀毒常相兼并见,肾虚毒蕴为其病机关键,治疗当扶正解毒,虚实兼顾。

We analyze the etiology and pathogenesis of HSPN （ Henoch-schonlein purpura nephritis ） in toxin terms, the main etiological factors of which are ＂heat toxin, hlood-stasis and toxin, damp toxin ＂.Heal toxin commonly exists in the early stage of HSPN, blood-stasis and toxin take part in the whole development process, damp toxin makes the course of the disease extended.Heat toxin, damp toxin, blood-stasis and toxin usually exist together.The key pathogenesis of HSPN is kidney deficiency and toxic substance accumulated, Traditional Chinese Medicine therapeutic method of the disease is to support vital-Qi and resolve toxin, in order to treat deficiency and excess syndrome at the same time.