家属的情感表达对分裂症患者服药依从性、病情复发及再住院的影响

The impact of different types of emotional expression of family members to patients with schizophrenia on the medication compliance, relapse and re-hospitalization

目的:探讨精神分裂症患者家属情感表达类型对患者服药依从性、病情复发及再住院的影响。方法:采用坎伯威尔家庭问卷中文版(CFI-CV)对符合入组标准的患者家属进行评定,选出80例高情感表达家庭的患者作为高情感表达组(HEE组),根据高情感表达组患者的性别和年龄进行1:1配对而选出80例低情感表达家庭的患者作为低情感表达组(LEE),对两组患者进行1年的随访,比较两组患者的服药依从性、病情复发及再住院情况。结果:HEE组患者在出院后半年及1年时的服药依从性均差于LEE组患者,两组在出院后半年的时间里病情复发及再住院无明显差异,但在出院后1年,HEE组患者的病情复发及再住院明显高于LEE组,复发相对危险度RR1=1.58,再住院相对危险度RR2=1.64;复发的率差RD1=17.5%,再住院的率差RD2=8.75%。结论:高情感表达会降低精神分裂症患者服药依从性,增加病情复发及再住院的风险。

Objective：To investigate the impact of different types of emotional expression of family members to patients with schizophrenia on the medication compliance, relapse and re -hospitalization. Methods：The family members were assessed in Camber well family interview - Chinese version （ CFI - CV）. 80 patients meeting the inclusion criteria whose family members were high emo- tional expression were divided into the high emotional expression （HEE） group. According to the gender and age of the patients in the high emotional expression, 80 patients meeting the inclusion criteria with low emotional expression family were divided into the low emo- tional expression （LEE） group. Both groups were followed up 1 year to compare the medication compliance, relapse and re - hospitali- zation. Results： The medication compliance of patients in HEE group is worse than in LEE group after six months and 1 year. There is no difference in relapse and re - hospitalization between both groups after six months. But the relapse and readmission of patients in HEE group was significantly higher than the LEE group in one year after discharge. The relapse and re - hospitalization relative risk arel. 58 and 1.64. The relapse and re- hospitalization rate difference are 17.5% and 8.75%. Conclusions： The high emotional ex- pression will reduce the medication compliance and increase the relapse and readmission risk.