家兔延髓嘴端腹外侧区向膈神经核的轴突投射

DESCENDING PROJECTIONS FROM THE ROSTRAL VENTROLATERAL MEDULLA TO THE PHRENIC NUCLEUS IN RABBITS

目的 :探讨家兔延髓嘴端腹外侧区与膈神经核之间的神经结构联系。方法 :用逆行标记方法 ,将CB HRP( 1% ,10 0nl)注入脊髓C5节段膈神经核内 ,观察延髓嘴端腹外侧区逆行标记神经元的分布。结果 :在面神经后核腹内侧区 (B tzinger复合体 )、旁巨细胞外侧核 (PGCL)观察到大量HRP逆行标记神经元。在斜方体后核观察到少数散在的标记神经元。结论 :膈运动神经元接受发自B tzinger复合体、PGCL的轴突投射。

Objective:To study the descending projections from the rostral ventrolateral medulla to the phrenic nucleus.Methods:Experiments were done on 10 pentobarbital anesthetized adult rabbit.After injection of CBHRP(1%)into the C 5 phrenic nucleus,a number of retrogradely labeled neurons were observed in the ventromedial area of the retrofacial nucleus(Bt.C),and nucleus paragigantocellularis lateralis(PGCL).Injection into control sites failed to label the neurons in the Bt.C and other respiratory related structures in the brainstem.Results:the phrenic nucleus receives monosynaptic axonal projections from the Bt.C and PGCL.Conclusion:these pathways may be involved in the control of respiration.