罗氏cobas e411与贝克曼DXI 800检测β-HCG结果比对分析被引量：1

Comparison of β-HCG Results between Roche cobas e411 and Beckman DXI 800 analysis systems

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摘要目的通过不同检测系统分析同一批患者标本,分析检测结果在不同线性范围内的相关性及临床符合情况。方法在罗氏cobas e411与贝克曼DXI 800上检测40例不同浓度水平患者标本,进行线性回归分析。结果人绒毛膜促性腺激素(β-HCG)在罗氏cobas e411线性范围内与贝克曼DXI 800线性范围内相关系数分别为0.998 3和0.995 5,两个检测系统检测结果临床符合率为100%。结论β-HCG在罗氏cobas e411与贝克曼DXI800上检测结果具有良好的相关性,临床诊断符合性一致。 Objective To discuss correlation between different analysis systems and clinical compatibility by examination of 40 patients′ specimens at different concentrations.Methods 40 patients′ samples were detected between Roche cobas e411 and Beckman DXI 800,results were statistically analyzed referring to EP9-2A.Results The corresponding correlation coefficient in Roche and DXI 800 linearity range were 0.998 3 and 0.995 5,results between two systems completely confirmed to clinical diagnostics.Conclusion β-HCG testing results have a good correlation and clinical compatibility between Roche cobas e411 and Beckman DXI 800 systems.

作者甘志彪陈卫布曹国磊李小龙

机构地区广东省深圳市人民医院检验科

出处《检验医学与临床》 CAS 2013年第2期165-166,共2页 Laboratory Medicine and Clinic

关键词人绒毛膜促性腺激素 COBAS e411 DXI 800 β-HCG cobas e411 DXI 800

分类号 R446 [医药卫生—诊断学]

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参考文献9

1CurranS,Dundas SR. Matrix metalloproteinase tissue inhibitors of matrix metalloproteinase phenotypt.identifies poor prognosis colorectal cancer[J].Clinical Cancer Research,2004,(24):8229.
2Gongoll S,Peters.G,Mengel M. Prognostic.Signifi-cance of Calcium-building.protein S100A4 in coloreetal cancer[J].Gastroenterology,2002,(05):1478.
3李佳.血绒毛膜促性腺激素β(血β-hcG)对早期诊断异位妊娠的探讨[J].中国卫生检验杂志,2007,17(6):1057-1058. 被引量：7
4马凤英.血清β2-HCG及孕酮测定在异位妊娠诊断中的意义[J]中国优生优育,2010(02):90-91.
5Cole LA. Immunoassay of humn chorionic gonadotropin,its free Subunits and metabolites[J].Clinical Chemistry,1997,(12):2233-2243.
6徐晓姹,吕时铭.人绒毛膜促性腺激素在体内的存在形式及其临床应用[J].国外医学（临床生物化学与检验学分册）,2005,26(11):815-818. 被引量：14
7王晓乐,邱潮林,嵇桃瑛,阮豪骥,张燕华,贾明.强生VITROS 3600全自动免疫分析仪检测血清β-HCG的临床应用评价[J].标记免疫分析与临床,2011,18(4):268-270. 被引量：6
8罗裕旋;何小媚;胡纪文.化学发光免疫分析法检测血清β-HCG中钩带效应分析[J]标记免疫分析与临床,2011(04):251-252.
9王庸晋.现代临床检验学[M]北京:人民军医出版社,2007608.

二级参考文献21

1赵映华,陈惠芳.血绒毛膜促性腺激素β对早期诊断异位妊娠的价值[J].中国妇产科临床杂志,2003,4(3):189-191. 被引量：4
2李佳.血绒毛膜促性腺激素β(血β-hcG)对早期诊断异位妊娠的探讨[J].中国卫生检验杂志,2007,17(6):1057-1058. 被引量：7
3马风英.血清β2-HCG及孕酮测定在异位妊娠诊断中的意义[J].中国优生优育,2010,:90-91.
4Spencer K, Talbot JA, Abushoufa RA. Maternal serum hyperglycosylated human chorionic gonadotrophin (HhCG) in the first trimester of pregnancies affected by Down syndrome, using a sialic acid-specific lectin immunoassay. Prenat Diagn, 2002, 22(8): 656-662.
5Stenman UH, Alfthan H, Hotakainen K. Human chorionic gonadotropin in cancer. Clin Biochem, 2004, 37(7): 549-561.
6Cole LA, Butler S. Detection of hCG in trophoblastic disease. The USA hCG reference service experience. J Reprod Med, 2002, 47(6): 433-444.
7Dirnhofer S, Freund M, Rogatsch H, et al. Selective expression of trophoblastic hormones by lung carcinoma: neurendocrine tumors exclusively produce human chorionic gonadotropin alpha-subunit (hCGalpha). Hum Pathol, 2000, 31(8): 966-972.
8Jobo T, Sato R, Kuramoto H. Tumor markers in gynecological and breast cancer. Rinsho Byori, 2003, 51(12): 1188-1194.
9Cole LA, Sutton JM. Selecting an appropriate hCG test for managing gestational trophoblastic disease and cancer. J Reprod Med, 2004, 49(7): 545-553.
10Skalba P, Gajewska K, Bednarska-Czerwinska A. Choriogonadotropina--krytyczna ocena nowych mozliwosci wykonywania oznaczen hormonu w diagnostyce medycznej [Choriogonadotropin measurements-critical assessment of new diagnostic possibilities]. Ginekol Pol, 2004, 75(3): 221-227.