骨髓病理检查在全血细胞减少性疾病中的应用价值

Clinical Value of Bone Marrow Histopathology in Pancytopenia Disease

目的探讨骨髓病理检查在全血细胞减少性疾病诊断及鉴别诊断中的临床价值。方法回顾性分析医院门诊及住院205例全血细胞减少性疾病患者临床资料。对患者在骨髓形态学检查的基础上加做骨髓病理检查。结果骨髓病理检查在再生障碍性贫血、骨髓增生异常综合征、骨髓纤维化、急性造血功能停滞、多发性骨髓瘤、骨髓转移癌、低增生急性白血病、缺铁性贫血的诊断价值明显优于骨髓形态学检查;同时发现骨髓病理对指导治疗有较好的临床价值。结论骨髓病理检查可作为全血细胞减少性疾病的诊断及鉴别诊断指标,亦有助于指导治疗。

Objective To investigate the clinical value of bone marrow histopathology in the diagnosis and differential diagno- sis to the pancytopenia disease. Methods The clinical data＇of 205 cases of pancytopenia（ inpatients and outpatient） were ana-lyzed retrospectively. The bone marrow samples were examined by histopathology. Results The diagnostic value of bone marrow histopathology examinations in aplastie anemia, myelodysplastic syndrome ,bone marrow fibrosis ,acute hematopoietic dysfunction, iron deficiency anemia,low proliferative acute leukemia, multiple myeloma and bone marrow metastases was super to bone marrow morphological examinations. Conclusion The bone marrow histopathology will probably indicate the activity of the diagnosis and differential diagnosis to the pancytopenia disease. The detection of serum fcrritin will be helpful to the therapeutic effect of anae-mia disease.