尘肺患者肺段灌洗治疗临床疗效观察

Clinical Effects of Bronchopulmonary Lavage in Patients with Pneumoconiosis

目的观察尘肺合并感染患者支气管肺段灌洗治疗临床疗效。方法选择70例急性期尘肺患者,随机分为实验组(35例)和对照组(35例)。两组同等病情住院期间接受常规治疗(抗感染、止咳祛痰平喘)。实验组在常规治疗的基础上加支气管肺段灌洗治疗,设计疗程为单个治疗疗程。观察两组患者支气管镜检结果、肺功能、血气分析各参数值变化,作统计学分析。结果实验组患者支气管镜检结果、肺功能、血气分析各参数指标与对照组比较差异有统计学意义(P<0.05),且无明显不良反应。结论尘肺患者支气管肺段灌洗治疗能有效改善尘肺急性加重期患者临床疗效指标,提高患者的生活质量。

Objective To observe the clinical effect of bronchopulmonary lavage therapy for the patients with pneumoconiosis complicated with infection. Methods All 60 acute stage patients with pneumoconiosis were randomly divided into the experimen-tal group（30 cases） and control group（30 cases）. Both groups received the conventional therapy such as anti-infection, antitus- sive, expectorant and antiasthmatic treatment; the experimental group also received the bronchopulmonary lavage treatment. The bronchoscopy findings, pulmonary function, blood gas analysis parameters in both groups were recorded and statistically analyzed. Results The differences in all tested parameters were statistical significance between the two groups （ P 〈 0.05 ）, and no obvious adverse reaction was found in the experimental group. Conclusion The bronchopulmonary lavage therapy can improve the clini-cal indicators in acute exacerbations of pneumoconiosis, and improve the QOL of patients.