早期乳腺癌保乳术与根治术的临床对照研究

Comparision of Breast-conserving Surgery and Modified Radical Mastectomy for Early Breast Cancer

目的比较保留乳房手术与改良根治术对早期乳腺癌预后的影响。方法回顾性分析安徽宿州市立医院肿瘤外科2005年6月-2011年6月经保留乳腺手术治疗的50例早期乳腺癌患者临床相关资料,并与同期在该科行改良根治术50例早期乳腺癌患者进行临床对比分析。结果保乳手术治疗不仅没有增加患者的局部复发率、转移率、病死率,且生存率与同期实施的改良根治术相当,并且保持了患者良好的乳房外形。结论在充分严格掌握保乳治疗适应证的前提下,规范手术方式,术后正规的辅助治疗如放化疗及内分泌治疗,不仅可治疗肿瘤,而且能明显提高患者的生活质量,是一种治疗早期乳腺癌比较理想的方法。实践证明对于早期乳腺癌,保乳手术是-种切实可行且值得推广的一种手术方式。

Objective To compare breast-conserving surgery and modified radical mastectomy for early breast cancer progno-sis. Methods Clinically relevant information of menstrual reserved breast surgical treatment of 50 patients with early breast cancer patients in Department of Surgical Ontology of Anhui Suzhou Municipal Hospital from June 2005 to June 2011 was com- pared with modified radical mastectomy with the same period in 50 patients, a retrospective analysis was conducted. Results Breast-conserving surgery did not increase in patients with local recurrence rate, metastasis rate, mortality and survival rates with the same period in the implementation of the modified radical mastectomy fairly, and kept well in patients with breast appearance. Conclusion To fully grasp the premise of breast-conserving treatment indications, standardize the surgical approach, formal post-operative adjuvant therapy, radiotherapy, chemotherapy and endocrine therapy, can not only treat tumor, but also significantly im-prove the quality of life of patients, the treatment was the ideal method of early breast cancer. Practice had proved that for early stage breast cancer, breast-conserving surgery was a surgical procedure-kind of practical and worth promoting.