期刊文献+

缺血性脑血管病患者颈动脉粥样硬化与TC、Lp(a)、DD、FIB、CRP水平相关性分析 被引量:8

下载PDF
导出
摘要 目的探讨缺血性脑血管病患者颈动脉粥样硬化与胆固醇(TC)、脂蛋白(a)(Lp(a))、D-二聚体(DD)、纤维蛋白原(FIB)、C反应蛋白(CRP)的相关性,以更好地对该病进行预防及治疗。方法对286例缺血性脑血管病患者采用颈动脉彩色多普勒检测颈动脉内中膜厚度(IMT),同时检测TC、Lp(a)、DD、FIB、CRP水平,并进行相关性分析。结果缺血性脑血管病合并颈动脉粥样硬化患者TC、Lp(a)、DD、FIB、CRP明显高于缺血性脑血管病无颈动脉粥样硬化患者(P均<0.01)。结论 TC、Lp(a)、DD、FIB、CRP可能与缺血性脑血管病患者颈动脉样硬化的发生有一定相关性,这些指标可能参与促进颈动脉粥样硬化斑块的形成。
作者 罗清艳
出处 《现代中西医结合杂志》 CAS 2013年第4期388-389,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine
  • 相关文献

参考文献9

二级参考文献36

  • 1程翔,廖玉华.炎症与动脉粥样硬化[J].中华心血管病杂志,2004,32(5):475-477. 被引量:86
  • 2各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33024
  • 3杨艳敏,李乃静,邱枫,田力,潘作东.血浆D-二聚体与老年短暂性脑缺血发作的关系[J].中国医学工程,2006,14(5):516-517. 被引量:5
  • 4刘昊,邓丽影,徐丽君.血管内皮损伤因子ACA、hsCRP与颈动脉斑块的关系[J].中国神经精神疾病杂志,2007,33(8):472-475. 被引量:12
  • 5McCully KS.Vascular pathology of homocysteinemia:implication for the pathogenesis of arteriosclerosis.Am J Pathal,1969,56:111 -128.
  • 6Libby P,Ridker PM,Maseri A.Inflammation and atherosclerosis.Circulation,2002,105:1135-1143.
  • 7Fujii H,Li SH,Szmitko PE,et al.C-reactive protein alters antioxidant defenses and promotes apoptosis in endot helial progenitor cells.Arterioscler Thromb Vasc Bio,2006,26:2476-2482.
  • 8Nabata A,Kuroki M,Ueba H,et al.Creactive protein induces endot helial cell apoptosis and matrix metalloproteinase-9 production in human mononuclear cells:lmplications for the destabilization of atherosclerotic plaque.Atherosclerosis,2008,196:129-135.
  • 9Van der bom JG,Bots ML,Haverkate F,et al.Activation products of the hemostatic system in coronary,cerebrovascular and peripheral arterial disease.Thromb Haemost,2001,85:234-239.
  • 10Mauriello A,Sangiorgi G,Palmieri G,et al.Hyperfibrinogenemia is associated with specific histocytological composition and complications of atherosclerotic carotid plaques in patients affected by transient ischemic attacks.Circulation,2000,101:744-750.

共引文献43

同被引文献60

  • 1解新荣,宁红霞,曹莹,勇彤,胡晓霞,王易娟,郝茹.短暂性脑缺血发作患者D-二聚体、纤维蛋白原水平的变化及其临床意义[J].脑与神经疾病杂志,2011,19(3):226-227. 被引量:15
  • 2秦华.缺血性脑血管病的药物治疗现状与进展[J].中国医药导刊,2013,15(S1):109-110. 被引量:8
  • 3各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33024
  • 4高月娟,张艳丽.曲美他嗪联合阿托伐他汀治疗不稳定型心绞痛38例分析[J].药物与临床,2012,50(4):66-67.
  • 5North American Symptomatic Endarterectomy Trial Collaborators. Beneficial effect of carotid endartereetomy in symptomatic patients with high-grade carotid stenosis [ J]. N Engl J Med, 1991 , 325 ( 7 ) :445-453. DOI : 10, 1056/NEJM199108153250701.
  • 6Mohammed N, Anand SS. Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recentneurological symptoms: randomized controlled trial. MRC asymptomatic carotid surgery trial (ACST) collaborative group. Lancet 2004; 363:1491-502 [ J ]. Vasc Med, 2005, 10 ( 1 ) : 77 -78.
  • 7Dong L,Underhill HR,Yu W,et al. Geometric and compositional appearance of atheroma in an angiographically normal carotid artery in patients with atherosclerosis [ J ]. AJNR Am JNeuroradio1,2010,31 (2) :311-316. DOI: 10.3174/ajnr. A1793.
  • 8Roger VL, Go AS, Lloyd-Jones DM, et al. Heart disease and stroke statistics-2012 update: a report from the American Heart Association[ J ]. Circulation, 2012,125 ( 1 ) : e2-e220. DOI: 10. II61/CIR. ObO13e31823 ac046.
  • 9Clarke SE, Beletsky V, Hammond RR, et al. Validation of automatically classified magnetic resonance images for carotid plaque compositional analysis[ J]. Stroke,2006, 37 ( 1 ) :93-97. DOI:10. 1161/01. STR. 0000196985. 38701.0c.
  • 10Biller J, Feinberg WM, Castaldo JE, et al. Guidelines for carotid endarterectom: a statemem for healthcare professionals from a Special Writing Group of the Stroke Council, American Heart Association[ J ]. Circulation, 2009,97 ( 5 ) : 501-509.

引证文献8

二级引证文献57

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部