摘要
成熟个体的心肌细胞不可再生 ,一旦受损只能由疤痕组织代替。心肌梗塞后残留心肌数量大量减少及继发心室重构是冠心病患者终末期心力衰竭的主要原因。成肌细胞、心肌细胞、直至平滑肌细胞被陆续移植入心脏 ,发现其均可存活并有助于提高心功能。但目前用细胞移植来提高有效心肌细胞数量的方法尚处于实验室研究阶段。
出处
《中国循环杂志》
CSCD
北大核心
2000年第3期188-189,共2页
Chinese Circulation Journal
参考文献4
-
1Reinecke H,Circulation,1999年,100期,193页
-
2Li R K,J Mol Cell Cardiol,1999年,31卷,513页
-
3Li R K,Ann Thorac Surg,1996年,62卷,654页
-
4Chiu R C J,Ann Thorac Surg,1995年,60卷,12页
同被引文献11
-
1Gerber HP,Hillan KJ,Ryan AM,et al.VEGF is required for growth and survival in neonatal mice[J].Development,1999,126 (6):1 149-1 159.
-
2Rosengart TK,Lee LY,Patel SR,et al.Angiogenesis gene therapy:phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF1231 cDNA to individuals with clinically significant severe coronary artery disease[J].Circulation,1999,100(5):468 -474.
-
3Paolo B,Pamela GR.Marrow stromal stem cell[J].J Clin Invest,2000,105 (12):1 663-1 668.
-
4Owen M.Marrow stromal stem cells[J].J Cell Sci Suppl,1998,10(1):63.
-
5EIGendi H,Violaris AG,Foale R,et al.Endogenous,local,vascular endothelial growth factor production in patients with chronic total coronary artery occlusions:further evidence for its role in angiogenesis[J].Heart,2002,87 (2):158-159.
-
6Zhang D,Gai L,Fan R,et al.Efficacy and safety of therapeutic angiogenesis from direct myocardial administration of an adenoviral vector expressing vascular andothelial growth factor 165[J].Chin Med J(Engl),2002,115(5):643 -648.
-
7Lee LY,Patel SR,Hackett NR,et al.Focal angiogen therapy using intramyocardial delivery of an adenovirus vector coding for vascular endothelial growth factor 121[J].Ann Thorac Surg,2000,69(1):14 -24.
-
8Friedenstein AJ,Gorskaja JF,Kalugina NN.Fibroblast precursors in normal and irradiated mouse hematopoietic organs[J].Experimental Hemateology,1976,4 (5):267-274.
-
9Makino S,Fukuda K,Miyoshi S,et al.Cardiomyocytes can be generated from marrow stromal cells in vitro[J].J Clin Invest,1999,103(5):697 -705.
-
10Wang JS,Shum-Tin D,Galipeau J,et al.Marrow stromal cells for cellular cardliomyoplasty:feasibility and potential clinical advantages[J].J Thorac Cardiovasc Surg,2000,120 (5):999-1 005.
引证文献1
-
1潘越江,华平,熊利华,王铭辉,杨艳旗,陈炬,张惠忠,张华,李佳.小鼠梗死心肌组织上VEGF基因治疗和骨髓间充质干细胞移植的实验研究[J].广西医学,2007,29(7):957-960. 被引量:1
-
1安秀娜.中西医结合治疗心肌梗塞近况[J].中医药动态,1994(1):29-29.
-
2郭翠英,上官青苗,田桂巧.静滴前列腺素E_1治疗心肌梗塞的观察与护理[J].长治医学院学报,1999,13(2):148-149.
-
3易静婷,刘丽群.倍他乐克治疗心肌梗塞临床效果观察[J].现代诊断与治疗,2015,26(17):4005-4006. 被引量:4
-
4魏向阳,王智杰,任旭爱.中西医结合治疗心肌梗塞65例临床分析[J].现代中医药,2003,23(5):19-20.
-
5张小玲,徐岩.国产尿激酶与进口重组链激酶治疗心肌梗塞比较[J].安徽医学,1998,19(5):22-23.
-
6张敏.探讨尿激酶在不同发病时间的心肌梗塞患者中的疗效[J].世界最新医学信息文摘,2014,14(22):66-66.
-
7梁月俊,王京慧,赵秋菊,许颖.大剂量尿激酶静脉溶栓治疗心肌梗塞疗效观察[J].实用医技杂志,1997,4(11):841-850.
-
8郭秋燕.前列腺素E_1治疗心肌梗塞30例分析[J].河南预防医学杂志,2000,11(5):300-300.
-
9张淑华,王津文.尿激酶溶栓治疗心肌梗塞的护理[J].河北中西医结合杂志,1998,7(6):977-978.
-
10张新莲.前列腺素E_1治疗心肌梗塞60例观察与护理[J].菏泽医学专科学校学报,1999,11(4):64-65.