摘要
异质性耐药,是指在同一样本中同时存在耐药菌和敏感菌的现象,这体现了细菌群体从部分耐药向完全耐药转变的过程。研究异质性耐药对于认识耐药结核病的发展过程,以及评估治疗方案和指导临床用药具有重要的意义。本文对结核分枝杆菌(Mycobacterium tuberculosis,MTB)异质性耐药的产生及其对临床的影响进行了综述。
Hetero-resistance is the coexistence of both sensitive and resistant bacteria in the same specimen, which indicates the transition from partially resistant to fully resistant bacterium population. Studying hetero-resistance is of great significance in understanding the genesis of drug-resistant tuberculosis, accessing the treatment schedule, and guiding the prescription of drugs. In this article, we summarized recent progresses on hereto-resistance of Mycobacterium tuberculosis （MTB）.
出处
《复旦学报（医学版）》
CAS
CSCD
北大核心
2013年第1期1-4,共4页
Fudan University Journal of Medical Sciences
关键词
结核分枝杆菌(MTB)
异质性耐药
耐药结核病
Mycobacterium tuberculosis （MTB）
hetero-resistance
drug-resistant tuberculosis
