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白细胞介素10对头颈部肿瘤作用的研究进展 被引量：1

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摘要 白细胞介素10(IL-10)作为一种免疫调节因子在头颈部肿瘤中的免疫抑制作用已被广泛研究,但近些年也有学者关于它的免疫作用提出了不同的看法。本文就IL-10与头颈肿瘤微环境、预后的关系、IL-10的正负调节作用等加以综述。
作者 周健 陶磊
机构地区 复旦大学附属眼耳鼻喉科医院耳鼻咽喉科
出处 《中国眼耳鼻喉科杂志》 2013年第1期54-56,共3页 Chinese Journal of Ophthalmology and Otorhinolaryngology
基金 国家自然基金青年基金(30801283) 上海市科委青年科技启明星(09QA1401000) 上海市卫生局优青计划(XYQ2011055)
关键词 白细胞介素10 头颈部肿瘤 肿瘤作用 IL-10 免疫抑制作用 免疫调节因子 肿瘤微环境 负调节作用
分类号 R739.91 [医药卫生—肿瘤]
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参考文献26

  • 1Chin D, Boyle GM, Porceddu S, et al. Head and neck cancer: past, present and future[J]. Expert Rev Anticancer Ther, 2006, 6 (7) : 1111-1118.
  • 2Whiteside TL. The tumor microenvironment and its role in promoting tumor growth[ J]. Oncogene, 2008,27 (45) :5904-5912.
  • 3Bergmann C, Strauss L, Wang Y, et al. T regulatory type 1 cells in squamous cell carcinoma of the head and neck: mechanisms of suppression and expansion in advanced disease [ J ]. Clin Cancer Res, 2008, 14(12) : 3706-3715.
  • 4Namyslowski G, Pilch J, Scierski W, et at. Interleukin-10 in laryngeal cancer patients treated by surgery or radiotherapy [ J ]. Otolaryngol Pol, 2006, 60(3): 325-330.
  • 5Gunaydin R, Kesikli SA, Kansu E, et at. Identification of the peripheral blood levels of interleukin-12, interleukin-10, and transforming growth factor-beta in patients with laryngeal squamous cell carcinoma [J]. Head Neck, 2012, 34(3) : 393-397.
  • 6Jebreel A, Mistry D, Loke D, et al. Investigation of interleukin 10,12 and 18 levels in patients with head and neck cancer [ J ]. J Laryngol Otol, 2007, 121 (3) :246-252.
  • 7Bolpetti A, Silva JS, Villa LL, et al. Interleukin-10 production by tumor infiltrating macrophages plays a role in Human Papillomavirus 16 tumor growth[J]. BMC Immunol, 2010, 11 : 27.
  • 8De Santo C, Arscott R, Booth S, et al. Invariant NKT cells modulate the suppressive activity of IL-10-secreting neutrophils differentiated with serum amyloid A [ J ]. Nat Immunol, 2010, 11 ( 11 ) : 1039-1046.
  • 9Ranelletti FO, Almadori G, Rocca B, et al. Prognostic significance of cyclooxygenase-2 in laryngeal squamous cell carcinoma [ J ]. Int J Cancer, 2001,95 (6) :343-349.
  • 10Stolina M, Sharma S, Lin Y, et al. Specific inhibition of cyclooxygenase 2 restores antitumor reactivity by altering the balance of IL-10 and IL-12 synthesis[J]. J Immunol, 2000, 164 ( 1 ) : 361-70.

同被引文献24

  • 1Vidwans SJ, Flaherty KT, Fisher DE, et al. A melanoma molecular disease model [J]. PLoS one, 2011, 6(3): e18257.
  • 2Thompson JF, Menzies SW, Shaw HM, et al. Cutaneous melanoma-Reply [J]. Lancet, 2005, 365(9476): 2004-2005.
  • 3Farias CF, Massaoka MH, Girola N, et al. Benzofuroxan derivatives N-Br and N-I induce intrinsic apoptosis in melanoma ceils by regulating AKT/BIM signaling and display anti metastatic activity in vivo[J]. BMC Cancer, 2015, 15: 807.
  • 4Kato Y, Yoshino I, Egusa C, et al. Combination of HDAC inhibitor MS-275 and IL-2 increased anti-tumor effect in a melanoma model via activated cytotoxic T cells[J]. J Dermatol Sci, 2014, 75(2): 140-147.
  • 5Cibulka M, Selingerova I, Fedorova L, et al. Immunological aspects in oncology-circulating gammadelta T cells[J]. Klin Onkol, 2015, 28 Suppl 2(2S60-68).
  • 6Kraan H, Vrieling H, Czerkinsky C, et al. Buccal and sublingual vaccine delivery[J]. J Control Release, 2014, 190(18): 580-592.
  • 7Azmi F, Ahmad Fuaad AA, Skwarczynski M, et al. Recent progress in adjuvant discovery for peptide-based subunit vaccines[J]. Human Vaccin Immunother, 2014, 10(3): 778-796.
  • 8Kashiwagi S, Brauns T, Gelfand J, et al. Laser vaccine adjuvants history, progress, and potential[J]. Human Vaccin Immunother, 2014, 10(7): 1892-1907.
  • 9Marciani DJ. Vaccine adjuvants: role and mechanisms of action in vaccine immunogenicity[J]. Drug Discov Today, 2003, 8(20): 934-943.
  • 10Kuo Ching S, Geoff AP, Mark DW, et al. Dendritic Cells: Activation and Maturation-Applications for Cancer Immunotherapy[J]. Curr Med Chem, 2005, 12(15): 1783-1800.

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中国眼耳鼻喉科杂志
2013年 第1期

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