扬州地区2010年乙型肝炎表面抗原阳性率调查

Investigation of the positive rate of hepatitis B surface antigen from Yangzhou in 2010

目的了解扬州地区的乙型肝炎病毒(hepatitis Bvirus,HBV)和表面抗原(hepatitis Bvirus surface antigen,HBsAg)阳性率,评价乙肝疫苗策略效果。方法以酶联免疫吸附试验(ELISA)检测HBsAg,将受检者以不同的年龄、性别分组计算HB-sAg的阳性率。结果 HBsAg的阳性率8.05%,41～50岁组的HBsAg的阳性率最高,达到10.38%,男性多年龄组HBsAg的阳性率高于女性且变化幅度较大。结论年龄和性别是乙肝感染的重要影响因素,注射乙肝疫苗的预防免疫在控制乙肝发挥了重大作用,乙肝的防治仍需重视。

Objective To investigate the positive rate of hepatitis B virus （ HBV ） surface antigen （ HBsAg ） in Yangzhou and evaluate the immune effect of hepatitis B vaccine.Methods HBsAg was detected by ELISA and calculate the positive rate of HBsAg grouped by age and sex respectively.Results The mean positive rate of HBsAg is 8.05% , the positive rate of HBsAg in the group of 41-50years old is the highest and is 10.38%and men′s is higher than women′s in most of age groups and change to a larger extent.Conclusion Age and sex is the important influence factors of HBV infection , vaccine played a major role in preventive im- mune to hepatitis B , it is still a important problem how to prevent and control hepatitis B perferably.