不同方式注射曲安奈德治疗黄斑水肿的眼压变化观察

Changes of intraocular pressure after intravitreal injection and posterior sub-tenon injection of triamcinolone acetonide the treatment of macular edema

目的探讨玻璃体腔注射(IVTA)和后Tenon囊下注射(PSTA)治疗黄斑水肿后的眼压变化情况。方法对167例黄斑水肿患者随机分为两组,分别采取IVTA和PSTA治疗,对比观察治疗后的眼压变化情况。结果 PSTA组平均眼压,高眼压发生率及6个月后残留高眼压率均明显低于IVTA组,P<0.05。结论 PSTA在眼压升高方面具有更好的安全性和耐受性。

Objective To compare changes of intraocular pressure（lOP） of intravitrcal injection and posterior sub-tenon injection of triameinolone acetonide on macular edema. Methods 167 patients of 167 eyes with maeuiar edema were randomized into two groups,intravitreal injection of triamcinolone acetonide group （IVTA group） and posterior sub-tenon injection of triamcin- olone aeetonide （PSTA group）. Changes of intraocular pressure were compared between the two groups. Results The PSTA group was obviously lower than the IVTA group in the mean IOP, the elevation lOP and tile residual elevation lOP ＇after 6 months. There was statistical difference. Conclusion The PSTA group was could be safer and more tolerability, in the elevation IOP.