静脉高氧液治疗心力衰竭及脑钠肽变化的临床研究

Clinical research of high oxygen liquid in the treatment of heart failure and brain hatriuretic peptide changes

目的:观察静脉高氧液对血浆脑钠肽水平的影响,评价高氧液对心力衰竭治疗的作用。方法:将入选的40例患者随机分为对照组、治疗组各20例。两组入院后均应用常规抗心力衰竭治疗,治疗组在常规治疗基础上输静脉高氧液,治疗两周酶联免疫吸附实验法测定血浆脑钠肽水平。结果:治疗组和对照组相比血浆脑钠肽水平下降明显(P<0.05);治疗效果比较差异有统计学意义。结论:在应用常规抗心力衰竭药物治疗的基础上联合静脉高氧液能降低血浆脑钠肽水平,明显改善心功能,静脉高氧液对心力衰竭有治疗促进作用。

Objective：To observe the venous hyperoxia liquid on plasma brain hatriuretic peptide levels,indirectly evaluate the effect of hyperoxia liquid on the treatment of heart failure and the role of nurses.Methods：40 patients were selected randomly divided into control group and treatment group,20 cases in each group.After admission,two groups were received conventional therapy,the treatment group used venous hyperoxia liquid based on the conventional treatment,the treatment for two weeks,enzyme-linked immunosorbent assay method for the determination of plasma brain hatriuretic peptide levels.Results：After treatment,the plasma brain hatriuretic peptide levels of two groups after treatment than before was decreased significantly（P0.05）;treatment and control groups compared to the plasma brain hatriuretic peptide levels decreased more significantly（P0.05）;compared of heart rate,blood pressure,the difference was statistically significant（P0.05）.Conclusion： Plus venous hyperoxia liquid to the conventional anti-heart failure drugs can lower plasma brain hatriuretic peptide levels,significantly improved cardiac function,venous hyperoxia liquid on the rest of the treatment of heart failure have a certain role.