期刊文献+

拉莫三嗪联合氟西汀治疗难治性抑郁症的临床疗效 被引量:6

Clinical Effect of Lamotrigine Combined with Fluoxetine in the Treatment of Refractory Depression
下载PDF
导出
摘要 目的对拉莫三嗪与氟西汀联合治疗难治性抑郁症的临床效果进行研究分析。方法抽取56例难治性抑郁症患者,将其分为对照组和治疗组各28例。对照组采用拉莫三嗪进行治疗;治疗组采用拉莫三嗪与氟西汀联合治疗。结果治疗组抑郁症改善效果明显优于对照组;治疗前后HAMD评分和TESS评分的改善幅度明显大于对照组;两组治疗期间没有出现不良反应。结论应用拉莫三嗪与氟西汀联合对患有难治性抑郁症的患者进行治疗的临床效果非常明显。 Objective To research and analyze the clinical effect of lamotrigine combined with fluoxetine in the treatment of refractory depression.Method 56 cases of patients with refractory depression were divided into control group and treatment group,28 cases in each group in average.Control group was treated with lamotrigine;Patients in the treatment group were treated with lamotrigine combined with fluoxetine.Results Patients in the treatment group was better than control group in the effect of improving depression;HAMD score and TESS score were improved significantly greater before and after treatment;There were no adverse reactions during treatment in the two groups.Conclusion The clinical effect is very obvious in the application of lamotrigine combined with fluoxetine in the treatment of refractory depression.
出处 《现代诊断与治疗》 CAS 2012年第11期1828-1829,共2页 Modern Diagnosis and Treatment
关键词 拉莫三嗪 氟西汀 难治性 抑郁症 Lamotrigine Fluoxetine Refractory Depression
  • 相关文献

参考文献3

二级参考文献17

  • 1Narushima K, Robinson RG. Stroke-related depression[J]. Curr Atheroscler Rep,2002,4(4) :296.
  • 2Gainotti G, Antonucci G, Marra C, et al, Relation between depression after stroke,antidepressant therapy , and functonal recovery[J]. J Neurosurg Psychiatry, 2001,71 : 258-261.
  • 3Starksein SE, Robinson RG, Price TK. Comparison of patients with and without poststroke major depression matched for size and location of lesion[J]. Arch Gen Psychiatry, 1998,45:247.
  • 4Bowles TM , I.evin GM. Aripiprazole: a new atypical antipsychotic drug[J]. Ann Pharmacother,2003,37(5):687.
  • 5Barbee JG, Conrad EJ, Jamhour NJ. Aripiprazole augmentalion in treatment-resistant depression[J].Ann Clin Psychiatry,2004,16(4) :189-194.
  • 6Worthington JJ , Kinrys G ,Wygant I.E , et al. Aripiprazole as an augmentor of selective serotonin reuptake inhibitors in depression and anxiety disorder patients[J].Int Clin Psychopharmacol,2005,20(1) :9-10.
  • 7陈彦方 顾牛范.新编临床精神药物手册[M].济南:山东科技出版社,1997..
  • 8Barbee JG,Conrad EJ,Jamhour NJ.Aripiprazole augmentation in treatment-resistant depression[J].Ann Clin Psychiatry,2004,16:189-194.
  • 9Worthington JJ,Kinrys G,Wygant IE,et al.Aripiprazole as an augmentor of selective serotonin rcuptake inhibitors in depression and anxiety disorder patients[J].Int Clin Psychopharmacol,2005,20:9-11.
  • 10Amsterdam JD,Hornig-Rohan M.Treatment algorithms in treatment-resistant depression[J].Psychiatr Clin North Am,1996,19:371-386.

共引文献111

同被引文献51

  • 1钟盈花,瞿正万.难治性抑郁症的临床特征、发病机制及治疗研究进展[J].中华临床医师杂志(电子版),2012,6(19):5995-5996. 被引量:11
  • 2汪春运.抗抽搐药治疗精神疾病[J].国际精神病学杂志,2006,33(3):170-174. 被引量:2
  • 3金卫东,陈炯,沈莹.拉莫三嗪对双相抑郁的治疗与预防[J].国际精神病学杂志,2006,33(4):231-234. 被引量:4
  • 4于欣,司天梅.精神药理学精要:处方指南[M].2版.北京:北京大学医学出版社,2009:131-136.
  • 5于欣,司天梅主译.精神药理学精要:处方指南[M].第2版.北京:北京大学医学出版社,2009:386.
  • 6Spom J, Sachs G. 1"ne anficonvulsant lamotrigine in treatment- resistant manic-depressive illness [J ]. J Clin Psychopharmacol,1997,17(3):185-189.
  • 7Marangell LB,Martinez JM,Ketter TA,et al. I_atmtrigine treatment of bipolar disorder:data from the first 500 patients in STEP-BD [ J]. Bipolar Disord,2004,6(2) :139 - 143.
  • 8Thase ME. What role do atypical antipsychotic drugs have in treatment-resistant depression? [ J ] . J Clin Psychiatry, 2002, 63( 2 ) :95 -103.
  • 9Amsterdam JD, Horning-Rohan M. Treatment algorithms in treatment-resistant depression [ J ]. Psychiatr Clin North Am, 1996,19(2) :371 -386.
  • 10刘兰英,马永春,金卫东,童振华.拉莫三嗪维持治疗双相心境障碍3例报道[J].精神医学杂志,2007,20(3):178-178. 被引量:2

引证文献6

二级引证文献30

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部