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2006-2010年贵港市HIV/AIDS患者合并机会性感染住院病人死亡相关因素分析 被引量:5

Analysis on death-related factors in patients with HIV/AIDS opportunistic infections in Guigang City from 2006 to 2010
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摘要 目的探讨HIV感染者/AIDS患者合并机会性感染住院患者死亡的危险因素。方法用回顾性调查方法,分析和比较2006-2010年贵港市人民医院住院的322例HIV/AIDS合并机会性感染住院患者中死亡病例和存活病例的人口学资料、临床特征和实验室检查,应用多因素Logistic回归分析探讨导致患者死亡的危险因素。结果 CD4+T淋巴细胞计数≤200×106/L(X1)和抗结核治疗不规范(X3)为HIV/AIDS合并机会性感染患者死亡危险因素,X1相应统计参数OR=9.381:1(4.939,17.818;95%CI。结论 CD4+T淋巴细胞计数与HIV/AIDS合并机会性感染患者的预后有一定的关联。 Objective To explore the risk factors of death from the people infected with HIV and AIDS patients in hospital with opportunistic infection. Methods Retrospective study was carried out and the demography, clinical and laboratory features of 322 patients with HIV/AIDS opportunistic infections admitted to the people' s hospital of Guigang from 2006 - 2010 were analyzed. Multifactorial analysis was done by using logistic regression to find the risking factors of death. Results The results of logistic regression showed that CD4~ T lymphocyte count ≤ 200 × 106/L (X1), Hb≤80g/L (X2) and non-standardized anti-TB treatment were the major risk factors of death, Conclusions There is a certain relation between CD4+ T lymphocyte count≤200 × 106/L (X1), Hb≤80g/L (X2) and non-standardized anti-TB treatment and HIV/AIDS with opportunistic infection patient' s prognosis.
出处 《应用预防医学》 2012年第6期332-335,共4页 Applied Preventive Medicine
基金 广西壮族自治区卫生厅重点课题(重2012052)
关键词 获得性免疫缺陷综合征 机会性感染 多因素分析 Acquired immune deficiency syndrome Opportunistic infections Multivariate analysis
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  • 1王爱霞,王福生,王清玥,王健,冯铁建,卢洪洲,孙洪清,孙永涛,叶寒辉,李太生,李兴旺,刘正印,邢玉兰,何云,汪宁,吴昊,吴南屏,张福杰,周曾全,宫恩聪,赵红心,赵敏,唐小平,徐莲芝,徐小元,曹韵贞,康来仪,蒋岩,蔡卫平,樊庆泊,潘孝彰.艾滋病诊疗指南[J].中华传染病杂志,2006,24(2):133-144. 被引量:630
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  • 4Thompson PM,Dutton RA,Hayashi KM. Thinning of the cerebral cortex visualized in HIV/AIDS reflects CD4+T lymphocyte decline[J].Proceedings of the National Academy of Sciences(USA),2010,(43):15647-15652.

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