摘要
目的探讨石河子地区不同年份及年龄、性别、民族的胃疾病患者中幽门螺杆菌(Hp)感染的差异。方法回顾性分析2007~2011年行胃镜检查并Hp染色病理学诊断的25 699例患者的临床资料。结果 25 699例胃镜检查患者中,Hp总的感染率为36.54%,2007~2011年各年份感染率分别为35.81%、35.03%、36.96%、36.80%、36.88%(P>0.01);男、女Hp感染率分别为38.10%、33.08%(P<0.01);汉族、哈萨克族的感染率分别为36.61%、50.91%(P<0.01);年龄12~20岁、21~30岁、31~40岁、41~50岁、51~60岁、61~70岁、71~89岁患者的感染率分别为28.57%、30.62%、35.36%、37.59%、44.46%、39.24%、29.37%(P<0.01),60岁之前随年龄增长感染率逐渐升高,至51~60岁者Hp感染率达高峰,之后呈下降趋势(P均<0.01)。慢性浅表性胃炎、慢性萎缩性胃炎、胃溃疡、十二指肠溃疡、复合溃疡和胃癌的Hp感染率分别为25.43%、49.08%、50.62%、64.74%、78.81%、19.46%(P<0.01)。结论新疆石河子地区25 699例胃镜检查患者Hp感染率为36.54%,低于全国自然人群平均感染率55.00%。不同民族、性别、年龄、胃疾病患者,其感染率均有差异。可能与当地气候及环境、医疗卫生等有关。今后应进行当地自然人群Hp调查,进一步研究影响Hp感染的因素,以期能够找到经济、有效的防治方案。
Objective To study the difference of Helicobacter pylori(Hp) infection in year,age,sex,nation,and stomach diseases in Shihezi region.Methods Clinical material of 25 699 patients who were examined by gastroscopy and Hp staining from 2007 to 2011 was retrospective analysised.Results The Hp infection rate was 36.54% in all 25 699 cases.The infection rate of each year from 2007 to 2011 was 35.81%,35.03%,36.96%,36.80% and 36.88%,respectively(P〉0.01).Hp infection rate in each age group of 12 to 20 years old,21 to 30 years old,31 to 40 years old,41 to 50 years old,51 to 60 years old,61 to 70 years old,71 to 89 years old was 23.69%,30.62%,35.36%,37.59%,44.46%,39.24% and 32.51%,respectively(P〈0.01).The Hp infection rate raised with age and peaked at 51 to 60 years old,hereafter descend gradually.The Hp infection rate was 38.10% in males and 33.08% in females(P〈0.01).The Hp infection rate of Hans and Hazakhs was 36.61% and 50.91%,respectively(P〈0.01).The Hp infection rate in chronic superficial gastritis,chronic atrophic gastritis,gastric ulcer,duodenal ulcer,compound ulcer and gastric cancer was 25.43%,49.08%,50.62%,64.74%,78.81% and 19.46%,respectively(P〈0.01).Conclusions The Hp infection is 36.54% in 25 699 cases examined by gastroscopy in Shihezi region.The Hp infection rate is lower than 55.00%,which was the average infection rate of nationwide natural crowd.Hp infection rate is different in sex,age,nation and diseases.The infection rate maybe correlated with the different climate,environment sanitation,public health,etc.It is necessary to inquire the Hp infection about nature crowd in the locality in order to find the way to prevent and cure Hp infection.
出处
《山东医药》
CAS
2012年第46期32-34,共3页
Shandong Medical Journal