甲状腺细针穿刺细胞学分析在甲状腺结节诊断中的应用

The value of fine-needle aspiration biopsy in diagnosis of thyroid nodus

目的:探讨甲状腺细针穿刺细胞学(fine-needle aspiration biopsy,FNAB)在甲状腺结节诊断中的应用价值。方法:对比分析94例甲状腺结节患者的FNAB与组织病理学检查结果。结果:94例甲状腺结节患者FNAB检测为良性病变81例,其中非肿瘤60例,腺瘤21例(病理证实乳头状腺瘤2例,滤泡状腺瘤19例);恶性病例9例,其中乳头状腺癌3例,未分化癌2例,腺癌4例(病理证实乳头状腺癌4例,髓样癌1例,未分化癌3例,滤泡状腺癌1例);未确定性4例(病理证实甲状腺滤泡状腺癌3例,甲状腺滤泡状腺瘤1例)。结论:FNAB对甲状腺结节的良恶性鉴别具有重要意义,对桥本甲状腺炎和亚急性甲状腺炎有确诊意义,准确掌握FNAB可提高甲状腺常见病的确诊率。

Objective：To analyze the value of fine-needle aspiration biopsy（FNAB） in diagnosis of thyroid nodus. Methods：A total of 94 cases with thyroid nodus were analyzed between FNAB and histopathology. Results：The results of FNAB analysis were shown：81 cases of benign lesion,including 60 cases of nontumorous changes and 21 cases of adenoma（the results of histopathology were that 2 cases of papillary adenoma,and 19 cases of follicular adenoma）;9 cases of malignant changes including 3 cases of papillary adenocarcinoma,2 cases of undifferentiated carcinoma and 4 cases of adenocarcinoma（the results of histopathology were that 4 cases of papillary carcinoma,1 case of medullary carcinoma,3 cases of undifferentiated carcinoma and 1 case of follicular adenocarcinoma）;and other 4 cases were unsuccessfully diagnosed by FNAB which reported that the glandular cells had obvious atypia,suggesting to do further examination（the results of histopathology were that 3 cases of follicular adenocarcinoma and 1 case of follicular adenoma）. Conclusions：FNAB plays an important role in identifing benign and malignant thyroid nodules,and diagnosing hashimoto thyroiditis and subacute thyroiditis definitely.The use of FNAB could improve the efficiency of definite diagnosis in common thyroid disease.