湖南省2009-2011年围产儿出生缺陷监测结果分析

Analysis on Monitoring Results of Perinatal Birth Defects in Hunan from 2009 to 2011

目的分析围产儿出生缺陷监测结果,探讨出生缺陷干预措施,降低出生缺陷发生率。方法对2009-2011年围产儿出生缺陷医院监测资料用SPSS软件进行统计分析。结果监测293 053例围产儿中,出生缺陷发生数5 766例,出生缺陷发生率为196.76/万,3年出生缺陷率差异有统计学意义(P<0.05)。前5位出生缺陷依次为:先天性心脏病、外耳其他畸形、多指(趾)、马蹄内翻足、唇裂合并腭裂。出生缺陷发生城市高于农村、孕母分娩无明显的季节分布、大于35岁组母亲出生缺陷发生率明显高于其他年龄组、男婴高于女婴。结论加强孕前、孕早期保健宣传,开展产前筛查、产前诊断和新生儿疾病筛查工作,避免和减少出生缺陷发生,提高出生人口素质。

Objective To analyze the moniloring results of perinatal birth defects and explore the interventions so as to re duce the incidence of birth defects. Methods SPSS software was used to analyze the monitoring data about birth defects among hcxspitals in Hunan from 2009 to 2011. Results A total of 293,053 perinatal infants were monitored. Birth defects occurred in 5,766 perinatal infants, and the incidence rate of birth defects was 196.76/10,000. There were statistically significant differences in the incidence rate of birth defects among the three years （P〈0.05）. The top 5 birth defects were congenital heart disease, auricular malformation, combined or excessive fingers or toes （polydaetyly）, elubfcx）t, cleft lip with cleft palate in turn. The incidence of birth defects was higher in urban areas than in rural areas, without significant sea,real distribution. The incidence rate of birth defects in the mothers aged 〉35 years was significantly higher than th{xse of other age groups. More male infants were involved than the female. Conclusions It is necessary to enhance health care propaganda before getting pregnant and during the early stages of pregnancy and popularize prenatal screening, prenatal diagnosis, and neonatal screening so as to avoid and reduce abnormal infants and improve the quality of births.