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烧伤患者外周血T淋巴细胞亚群表达与炎性标志的分析 被引量:3

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摘要 目的探讨烧伤患者外周血T淋巴细胞亚群表达以及炎症标志指标的相关变化。方法根据烧伤面积程度将烧伤患者分为重度烧伤组和轻度灼伤组(包括电击伤、烫伤),对照组为体检健康者。采用流式细胞仪的单克隆抗体分析细胞免疫指标[CD3、CD4、CD8、CD19、自然杀伤细胞(NK细胞)],采用散射比浊法分析炎症因子指标[C反应蛋白(CRP)、α-酸性糖蛋白(AAG)、结合珠蛋白(HP)、铜蓝蛋白(CER)],观察细胞免疫指标(CD3、CD4、CD8、CD19、NK细胞)和炎症因子指标(CRP、AAG、HP、CER)的变化。结果重度烧伤患者的各项免疫指标与对照组比较差异有统计学意义(P<0.05);而轻度灼伤患者各项免疫指标无明显异常。重度烧伤组CRP,AAG,HP、CER和轻度灼伤组HP、CER、HP与对照组比较差异有统计学意义(P<0.05)。结论外周血T淋巴细胞亚群表达以及炎症标志指标检测对临床烧伤患者的诊断、治疗和病情监测至关重要。
出处 《国际检验医学杂志》 CAS 2012年第20期2481-2482,共2页 International Journal of Laboratory Medicine
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参考文献5

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