腹水染色体联合ADA及CEA检测对腹腔恶性肿瘤的诊断价值

Ascites combined with ADA and CEA chromosome detection of abdominal malignant tumor diagnosis value

目的探讨腹水染色体检测联合腺苷脱氢酶(ADA)、腹水癌胚抗原(CEA)检测在腹腔良恶性肿瘤诊断中的应用价值。方法将到该院就治的125例胸腹水患者根据临床病理学诊断结果分为良性肿瘤组及恶性肿瘤组,两组患者均行染色体检测、ADA及CEA检测,将两组患者的染色体检测、ADA及CEA检测结果进行比较。结果腹腔恶性肿瘤患者DI>2.5的异倍体细胞数量比良性肿瘤患者多;恶性肿瘤患者ADA含量比良性肿瘤患者少;恶性肿瘤患者CEA含量比良性肿瘤患者多;两组上述指标比较差异均具有统计学意义(P<0.05)。结论腹水染色体、ADA及CEA3种检测方法结合,能有效提高恶性肿瘤的诊断正确率,值得临床广泛推广。

Objective To explore the ascites chromosome detection combined with adenosine dehydrogenase（ADA） ,ascitic fluid carcinoembryonic antigen（CEA） detection in peritoneal malignant and benign tumor diagnosis application value. Methods To the hospital for treatment of 125 cases of pleural effusion and ascites patients according to clinical pathological diagnosis was classified as benign tumor group and the malignant tumor group, two patients underwent ADA and CEA chromosome detection, detection, two groups of patients with chromosome detection,ADA and CEA results were compared. Results Patients with abdominal malignant tumor DI〉2.5 heteroploid cell number were move than benign tumor patients; patients with malignant tumor patients with benign tumors were less than ADA content in patients with malignant tumor CEA content was mere than patients with benign tumors ; two groups of the indices were statistically significant difference （P〉 0.05）. Conclusion Ascites chromosome, ADA and CEA three detection methods,can imorove the correct diagnostic rate of malignant tumors,is worthy of clinical application.