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Effects of endogenous L-cystathionine on enzymatic assays of serum homocysteine in samples from renal dialysis patients

Effects of endogenous L-cystathionine on enzymatic assays of serum homocysteine in samples from renal dialysis patients
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摘要 Homocysteine (Hcy) is a thiol-containing amino acid produced by the intracellular demethylation of methionine.Approximately 80% of circulating Hcy in the blood is protein bound by disulfide linkage.The remaining unbound Hcy combines by oxidation either with itself to form the dimer homocystine or with cysteine to form the mixed disulfide cysteine-Hcy. Homocysteine （Hcy） is a thiol-containing amino acid produced by the intracellular demethylation of methionine.Approximately 80% of circulating Hcy in the blood is protein bound by disulfide linkage.The remaining unbound Hcy combines by oxidation either with itself to form the dimer homocystine or with cysteine to form the mixed disulfide cysteine-Hcy.
作者 Chen Zhaojun Zhang Lahong Pan Feng Zheng Gaoming Li Huan Gao Li Michael Nicolaou
机构地区 Department of Laboratory Nicopharm Pharmaceutical Solutions Inc.
出处 《国际检验医学杂志》 CAS 2012年第24期2969-2973,共5页 International Journal of Laboratory Medicine
关键词 氨基酸蛋氨酸 细胞 血液 医学研究 cysteine serum renal dialysis cystathionine
分类号 R692.5 [医药卫生—泌尿科学]
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参考文献14

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国际检验医学杂志
2012年 第24期

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