深静脉血栓模型动物下腔静脉的应力松弛

Stress relaxation properties of an animal model of inferior vena cava thrombosis

背景:应力松弛是下腔静脉的重要黏弹性指标,以往这方面的研究未见报道。目的:比较正常动物下腔静脉和老龄深静脉血栓动物模型下腔静脉的应力松弛特性。方法:在日本岛津电子万能实验机上,对正常动物下腔静脉和老龄深静脉血栓动物模型下腔静脉各10个试样进行应力松弛实验。应力松弛实验应变增加速度为1%/s,设定时间为7200s,采集100个数据,以统计分析和回归分析的方法处理实验数据。结果与结论:正常对照组试样7200s应力松弛量为0.0268MPa,模型组试样7200s应力松弛量为0.023MPa,两组比较差异有显著性意义(P<0.05)。应力松弛曲线是以对数变化的,应力松弛最初600s变化较大,之后应力缓慢下降,达到7200s时应力松弛曲线基本水平。结果可见老龄深静脉血栓下腔静脉应力松弛力学特性发生了改变,深静脉血栓对下腔静脉应力松弛特性具有一定影响。

BACKGROUND：Stress relaxation is an important the viscoelastic indicator of the inferior vena cava,and relevant studies have not been reported yet.OBJECTIVE：To compare the stress relaxation properties of the inferior vena cava between the normal animals and the aged models of deep vein thrombosis.METHODS：A total of 20 samples of the two groups underwent stress relaxation test on the AG-10TA universal material testing machine.Strain acceleration was 1%/s.The duration of the test was 7 200 seconds.Total 100 data were collected and analyzed.Regression analysis was applied to process data.RESULTS AND CONCLUSION：The stress relaxation at 7 200 seconds was 0.026 8 MPa and 0.023 MPa,respectively,in the normal control group and model group.There was a significant difference between the two groups（P〈0.05）.The stress relaxation curve followed the logarithmic relationship.The stress relaxation changed best within the first 600 seconds,then decreased gradually and reached the basic level at 7 200 seconds.The stress relaxation properties were affected in the aged animals of inferior vena cava thrombosis,and deep vein thrombosis had a certain effect on the stress relaxation properties of the inferior vena cava.