不同粒径淫羊藿中化学成分溶出度比较研究

Comparative Study on the Dissolution Rate of Chemical Composition in Different Size Epimedium

本试验通过用超声法和浆状搅拌法提取不同目径淫羊藿中淫羊藿苷和总黄酮,分别用高效液相色谱法和紫外分光光度法测定其溶出量和溶出速率。结果表明,粒径越细,其溶出速率和溶出总量都在增加,400目时其溶出量达到最大,但粉碎到500目时,其溶出速率和溶出总量反而不及300目,因此淫羊藿超微粉的应用以400目效果最好。

Comparing the difference of dissolution rate and total dissolution of icarii and flavonoids in different size herba epimedii.The icarii and flavonoids in the herba epimedii were determined by HPLC and UV spectrophotometer.The results showed that the dissolution rate and total dissolution of icarii and flavonoids in herba epimedii were increased when the size was more slim,and the dissolution of 400 mesh was the most.Compared with 300 mesh,the dissolution rate and total disslution of 500 mesh were reduced.Therefore,the 400 mesh was the best for herba epimedii.