儿茶酚胺敏感性多形性室性心动过速

Catecholaminergic polymorphic ventricular tachycardia

儿茶酚胺敏感性多形性室速(CPVT)是一种是好发于青少年的遗传性心律失常综合征,其核心是由肾上腺素所诱发的心律紊乱。其典型的临床特征是运动或情绪激动时诱发室性心动过速,常伴发晕厥,甚至发生猝死。对于既往有晕厥或室速发作的患者,应当坚持使用β-受体阻滞剂(Ⅰa类证据),CPVT患者发生过心脏骤停为埋藏式心脏转复除颤器(ICD)治疗的Ⅱa类适应证。

Catecholaminergic polymorphic ventricular tachycardia （CPVT）, induced by adrenergic stress, is an inherited car- diac arrhythmia syndrome mostly found in adolescence. Patients with CPVT typically present with exercise- or emotion-in- duced ventricular arrhythmia leading to onset of syncope or sudden cardiac death. Beta-blockers are strongly indicated （ I a） for patients with clinically-diagnosed CPVT based on the previous history,whereas intracardiac defibrillator implantation is recommended for those with CPVT who previously experienced cardiac arrest.