乳腺癌乳房切除术后局部区域复发的研究现况

Research status for Iocoregional recurrence of breast cancer after mastectomy

乳腺癌在乳房切除术后出现局部区域复发（LRR），虽是疾病进展的一个信号，但LRR不同于远处转移。其中部分患者经积极治疗后仍预后较好，尤其是孤立的LRR患者。复发间隔、复发位点和复发灶数目等对LRR患者预后有较大影响。对适合的LRR患者，手术切除和内分泌治疗的价值已被证实，化疗的价值仍有待进一步研究。

Although locoregional recurrence （LRR） after mastectomy is regarded as a signal of disease progression, but it is different from distant metastasis. Some patients could have better prognosis and benefit from salvage treatments, especially for patients with isolated LRR. Time to recurrence, site of recurrence and number of recurrent nodules have great influence on the prognosis of patients with LRR. For suited patients with LRR, surgical resection and endocrine therapy are valuable in suitable cases, but the role of chemotherapy still need further study.