特发性肺纤维化合并肺癌诊治进展

Progress in diagnosis and treatment of lung cancer complicated by idiopathic pulmonary fibrosis

肺癌是目前发病率最高的恶性肿瘤，有报道特发性肺纤维化（IPF）是肺癌的一个危险因素。IPF合并肺癌临床表现、影像学具有其特点。合并有IPF的肺癌治疗难度大，不论手术还是放化疗发生急性加重的风险均高于其他患者，而且预后较差。

It is reported that the incidence of lung cancer in patients with pulmonary fibrosis is higher than that in general population. The patients presented with idiopathic pulmonary fibrosis and lung cancer （IPF-LC） have different clinical features and radiological manifestations. Regardless of whether the operation or chemotherapy, the risk of acute exacerbations for IPFLC is higher than other patients. These patients with IPF-LC have poor prognosis and deteriorate within a few years.