服用盐酸氯吡格雷后中性粒细胞减少的相关性分析

Taking Hydrochloric Acid after Clopidogrel Neutropenia Correlation Analysis

目的:研究冠心病患者服用盐酸氯吡格雷后中性粒细胞减少的相关因素。方法:以内蒙古包钢医院2010年1月～12月间住院患者中患冠心病并服用盐酸氯吡格雷者为研究对象,检查服药前后中性粒细胞变化,分为减少组和正常组进行比较。结果:其242例研究对象中中性粒细胞减少组27例,发生率11.15%单因素分析结果显示抗糖尿病药物、吸烟、饮酒3个方面,中性粒细胞减少组和正常组比较具有统计学意义,(P<0.05)。结论:糖尿病、饮酒和吸烟是白细胞减少的相关性因素。

Objective：to study the coronary heart disease patients take hydrochloric acid after clopidogrel neutropenia related factors.Methods：to Inner Mongolia baotou hospital in January 2010-12 month in hospitalized patients with coronary heart disease and taking hydrochloric acid clopidogrel person as the research object,check before and after medication neutrophils change,divided into reduce group and normal group comparison.Results：242 cases of the research object of neutropenia group and an example,11.15% incidence of single factor analysis results show that the resistance to diabetes drugs,smoking,drinking three aspects,neutropenia group and normal group compared with the statistical significance（P 0.05）.Conclusion：Diabetes,drinking and smoking is leucopenia correlation factors.