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CD133及CD166在脑膜瘤中的表达及临床意义 被引量:6

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摘要 目的:探讨CD166与现在公认的脑肿瘤干细胞标记物CD133在不同级别脑膜瘤组织中的表达情况及其意义。方法:采用免疫组织化学技术检测CD133和CD166在80例脑膜瘤组织石蜡切片中的表达情况。结果:CD133和CD166均表达于细胞膜和细胞质,呈散在或簇状聚集分布。CD133、CD166的积分光密度(IOD)值在不同病理级别脑膜瘤中差异有显著性(Z=-4.080,P=0.000;Z=-4.657,P=0.000),二者表达随着病理级别的增高而增高,二者表达呈显著正相关(r=0.706,P=0.000)。结论:CD133与CD166表达与组织病理级别密切相关,CD166可能是脑膜瘤干细胞标记物之一。
出处 《实用医学杂志》 CAS 北大核心 2013年第3期413-415,共3页 The Journal of Practical Medicine
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