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中性粒细胞趋化三肽在慢性阻塞性肺疾病中的作用机制 被引量：1

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摘要 慢性阻塞性肺疾病（COPD）在研究和治疗上最主要的障碍是缺乏一种与疾病的严重程度和评价预后相关的标志物。近年发现，
作者 贾晔然 张红璇
机构地区 南方医科大学 广东省人民医院平洲分院
出处 《实用医学杂志》 CAS 北大核心 2013年第3期501-503,共3页 The Journal of Practical Medicine
关键词 慢性阻塞性肺疾病 中性粒细胞 趋化三肽 预后相关 标志物
分类号 R563.9 [医药卫生—呼吸系统]
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参考文献18

  • 1Yoon H I,Sin D D. Biomarkers of therapeutic response in patients with chronic obstructive pulmonary disease:a critical review of the literature[J].Drugs,2011,(14):1821-1837.
  • 2Pfister R R,Haddox J L,Sommers C I. Identification and synthesis of chemotactic tripeptides from alkalidegraded whole cornea.A study of N-acetyl-proline-glycine-proline and N-methyl-proline-glycine-proline[J].Investigative Ophthalmology & Visual Science,1995,(07):1306-1316.
  • 3Pfister R R,Haddox J L,Sommers C I. Injection of chemoattractants into normal cornea:a model of inflammation after alkali injury[J].Investigative Ophthalmology & Visual Science,1998,(09):1744-1750.
  • 4O'Reilly P J,Gaggar A,Blalock J E. Interfering with extracellular matrix degradation to blunt inflammation[J].Current Opinion in Pharmacology,2008,(03):242-248.
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同被引文献7

  • 1慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华结核和呼吸杂志,2007,30(1):8-17. 被引量：8227
  • 2VaJay G G, Franitza S, Schor H. Combinatorial signals byinflammatory cytokines and chemokines mediate leukocyte interactions with dextracellular matrix [J]. J Leukoc Biol, 2001,69(6) :885-892.
  • 3Chen H, Wang D, Wang X. Role of Airway Epithelium-Origin Chemokines and their Receptors in COPD [J]. Journal of Epithelial Biology & Pharmacology, 2010,3 : 26-33.
  • 4LEE S C, Brummet M E, Shahabuddin S, et al. Cutaneous injection of human subje-cts with ifflammatory protein-I alpha induces signific-antrecruitment of neutriphils and monecyets[J. J Inmmnol, 2000,164(6) : 3392-3401.
  • 5Sehmelzer C, Lorenz G, Rimbach G, et al. In vitro effects of the reduced form of coengynle QlO on secretion levels of TNF-a and chemokines in response to LPS in the human monocytic cell line THP- 1 [ J ]. JClin Biochem Nutr, 2009,44 ( 1 ) : 62-66.
  • 6Salvatore C M, Techasaensiri C, Taliabue C, et al. Tigecycline therapy significantly reduces the concentrations of inflammatory pulmonary cytokines and chemokines in a murine model of mycoplasma pneumonia pneumonia [J]. Antimicrob Agents Chemother, 2009,53 (4) : 1546-1551.
  • 7高占成.降钙素原对诊断慢性阻塞性肺疾病急性加重的应用价值[J].中华结核和呼吸杂志,2013,36(4):313-314. 被引量：34

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实用医学杂志
2013年 第3期

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