三组分一锅法合成(E)-β-(烷氧基)苯乙烯

Three-Component One-Pot Synthesis of (E)-β-(Alkoxy)arylethylenes

以苄基醇、二甲亚砜(DMSO)和烷基醇为原料,采用三组分一锅法合成了一系列(E)-β-(烷氧基)苯乙烯类化合物。该法具有产率高(68%～82%)、操作简单、后处理方便等优点。产物的结构通过核磁共振谱和元素分析证实,同时给出了可能的反应机理。

A series of （E）-β-（alkoxy） arylethylenes was synthesized by the one-pot three-component reaction of substituted benzyl alcohol, dimethyl sulfoxide and alkyl alcohols under mild conditions. This method has the advantages of high yields（68% - 82% ） and simple workup. The structures of the products were identified by 1H NMR, 13C NMR spectra and elemental analysis. In addition, the probable mechanism for the reaction was proposed.