散发性戊型肝炎32例临床分析

Clinical analysis of sporadic hepatitis E in 32 cases

目的:分析戊型肝炎的临床特点。方法:回顾性分析32例戊型肝炎患者的临床特点和生化指标差异。结果:所有戊型肝炎患者中黄疸30例,发热5例,无症状1例,抗-HEV IgM阳性16例,抗-HEV IgG阳性24例,两抗体均阳性者2例,重叠乙肝2例。结论:戊型肝炎以老年多发,以急性黄疸型为主,春季为多发季节,同时检测抗-HEV IgM和抗-HEV IgG抗体以免漏诊和误诊,预后良好。

Objective： To analyze the clinical characteristics of hepatitis E. Methods ： Retrospective analysis was performed in 32 cases of hepatitis E regarding the clinical features and differences in laboratory findings. Results：Jaundice was seen in 30 cases, fever in 5 and asymptomatie carrier in 1. Of the total 32 cases, 16 were positive for HEV IgM antibodies and 24 for HEV IgG antibodies. Two cases were positive for the two antibodies, and another 2 were associated with hepatitis B. Conclusion ： Hepatitis E occurs more often in the elderly, presenting with acute jaundice and higher seasonal prevalence in spring. Detection of both antibodies of HEV IgM and HEV IgG can prevent from missed diagnosis and misdiagnosis. Prognosis for this disease is better in general.