心理干预对产妇产后抑郁影响的Meta分析

目的探讨心理干预对产妇产后抑郁的影响。方法采用RevMan5.1.6软件进行数据分析,两组之间差异采用标准均数差(standardized mean difference,SMD)及其95%可信区间(95% confidence interval,95%CI)描述。最终纳入9个临床对照试验,共560名产后抑郁的妇女,其中心理干预组280例,对照组280例。结果干预前,心理干预组与对照组产后抑郁患者SDS评分无明显差异(SMD=-1.38,95%CI:-7.03～4.26,P=0.63);干预后,心理干预组患者SDS评分显著低于对照组患者,两组之间差异有统计学意义(SMD=-15.37,95%CI:-23.37～-7.36,P=0.0002)。结论积极的心理干预可有效地改善产后抑郁症,降低产妇产后抑郁症的发生率。

Objective To investigate the effects of psychological intervention on postpartum depression. Methods Data analysis was conducted by RevMan 5.1.6 software. The difference between the groups was described using SMD and 95%CI. Finally, 9 clinical controlled trials were selected eventually including 560 cases with postpartum depression. All cases were divided into psychological intervention group and control group, 280 cases in each group. Results Meta-analysis results showed that there was no significant difference between two groups in pre-intervention SDS scores （SMD=-l.38, 95%CI： -7.03-4.26, P=0.63）. However, post-intervention SDS scores （SMD=-15.37, 95%CI： -23.37-7.36, P=0.0002） had has statistically significant differences. The score of psychological intervention group is lower significantly than control group. Conclusion Psychological intervention may impact on relieving depressive symptoms for puerpera and decreasing the rate of postpartum depression.