经皮穴位电刺激复合瑞芬太尼靶控输注用于甲状腺手术的临床研究

Clinical research of transcutaneous electrical acupoint stimulation combined with target-controlled infusion of Remifentanil in thyroid surgery

目的观察经皮穴位电刺激复合瑞芬太尼靶控输注用于甲状腺手术的临床效果。方法选择60例择期行单纯甲状腺切除术患者,将其随机分为观察组和对照组,各30例。两组患者均给予瑞芬太尼靶控输注,观察组加用经皮穴位电刺激。比较两组患者切皮时所需的瑞芬太尼目标血浆浓度、心血管应激反应以及术口疼痛、恶心、呕吐、镇静等差异。结果观察组患者的心血管反应和术口疼痛均明显优于对照组患者(P<0.05),对照组需用较多的瑞芬太尼。结论经皮穴位电刺激联合瑞芬太尼用于甲状腺手术镇痛效果较好,心血管应激反应较小,临床效果满意。

Objective To study the clinical effect of transcutaneous electrical acupoint stimulation combined with tar- get-controlled infusion of Remifentanil in thyroid surgery. Methods 60 patients undergoing elective thyroidectomy were chosen and randomly divided into observation group and control group, with 30 cases in each group. Both groups were given target-controlled infusion of Remifentanil, while observation group was added with transcutaneous electrical acupoint stimulation. The differences of the target plasma concentration of Remifentanil, cardiovascular stress reaction and the pain of operation mouth, nausea, vomiting, calm of the two groups were compared. Results The cardiovascular reverse and the pain of operation mouth in observation group were significantly superior to control group （P 〈 0.05）, and the control group needed more Remifentanil. Conclusion The effect of transcutaneous electrical acupoint stimula- tion combined with target-controlled infusion of Remifentanil in thyroid surgery is good and cardiovascular stress reac- tion is less, the clinical effect is satisfcatory.