摘要
阿尔茨海默病(AD)是以认知功能障碍和记忆损害为主要临床特征的神经退行性疾病,多发于老年人。其病因复杂,导致缺乏有效的诊断、治疗和预防手段。目前,β淀粉样蛋白(Aβ)被认为是AD免疫治疗的关键靶标。研究表明,Aβ可能是各种原因诱发AD的共同通路,是AD形成和发展的关键因素。通过结合文献并对近年来阿尔茨海默病的免疫治疗方法进行探讨。
Alzheimer's disease(AD) is a progressive neurodegenerative disorder in the aged,which is characterized with pathological dementia and memory damage in chnic.Due to its complex causes,there is no effective method to diagnose, prevent and treat.Recently,βamyloid(Aβ),the key factor in the formation and development of AD,is considered as the common path of various AD leading causing.Combined literatures,this article summarized immunotherapy for Alzheimer's disease in these years.
出处
《中华中医药学刊》
CAS
2013年第1期60-62,共3页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金资助项目(30973700
81173265)
关键词
阿尔茨海默病
Β淀粉样蛋白
免疫治疗
Alzheimer's disease
βamyloid
immunotherapy
active immunity
passive immunity