重度阻塞性睡眠呼吸暂停低通气综合征压力滴定方式的探讨

Research of CPAP pressure titration methods for serious obstructive sleep apnea hypopnea syndrome

目的通过两种压力滴定技术的比较,探讨重度阻塞性睡眠呼吸暂停低通气综合征的最佳压力滴定方式。方法将60例愿意接受压力滴定的重度阻塞性睡眠呼吸暂停低通气综合征患者随机分为实验组和对照组各30例,实验组使用手工压力滴定技术;对照组使用自动压力滴定技术。两组治疗后进行多导睡眠图各项参数比较。结果与治疗前比较,实验组治疗后呼吸暂停低通气指数、最低血氧饱和度、<90%的氧减时间等参数均有明显改善;与对照组治疗后比较,实验组治疗后各项参数差异有显著意义。结论重度阻塞性睡眠呼吸暂停低通气综合征应首选手工压力滴定技术。

Objective To study the better continuous positive airway pressure （CPAP） titration method of seri- ous obstructive sleep apnea hypopnea syndrome by the comparison of CPAP pressure titration methods. Method 60 patients with obstructive sleep apnea hypopnea syndrome （OSAHS） willing to get CPAP pressure titration was di- vided into experimental group and control group. Both groups have 30 patients. The patients in experimental group were carried on manual pressure titration,while the patients in control group were carried on automatic pressure ti- tration. PSG parameters after treatment for the two groups was observed and compared. Result Compare with that before treatment, apnea hypopnea index,lowest oxygen saturation and the percentage of recording time with oxygen saturation of 90% or less in experimental group were better than the control group after treatment. Compare to con- trol group, there was significant difference in PSG parameters of experimental group after treatment. Conclusion Manual pressure titration will be the first chose for the treatment of serious obstructive sleep apnea hypopnea syn- drome.