耐甲氧西林金黄色葡萄球菌的临床分布与耐药性分析

The Clinical Distribution of Methicillin-resistance Staphylococcus Aureus and Its Drug-resistance Pattern

目的:探讨绵阳市中心医院耐甲氧西林金黄色葡萄球菌(MRSA)临床分布及耐药特征,指导临床合理用药。方法:利用LIS系统,对绵阳市中心医院2010年6月-2011年6月分离出的80株MRSA的临床分布和耐药谱进行回顾性分析。结果:MRSA占金黄色葡萄球菌的21%,MRSA对临床常用抗生素具多重耐药性,MRSA侧重于儿科、耳鼻喉科、骨科、ICU及胸外等病房,主要存在于创面分泌物、痰、血液、脓等送检标本中。结论:MRSA耐药谱广,在一些发达国家已经将MRSA与烈性传染病同等对待,所以应引起临床的广泛关注。

Objective：To study the distribution and drug resistance of methicillin-resistant-Staphylococcus aureus（MRSA） isolated from the central hospital of Mianyang city,to guide clinical reasonably uses antibiotics.Methods：LIS system was used to identify and analyze 80 MRSA samples obtained from the central hospital of Mianyang during June 2010 to June 2011.A retrospective study was done for its clinical distribution.Results：MRSA accounted for 21% in Staphylococcus aureus,MRSA had multiple drug resistance to antibiotics that commonly used,that samples mainly isolated from wards of pediatric,Otorhinolaryngology,orthopedics,ICU and chest surgery,in addition,mainly exists in wound secretion,phlegm,blood,pus and so on.Conclusion：MRSA had Extensively drug-resistant,in some countries it is treated as same as serious contagion,so great attention should be paid.