摘要
目的探讨慢性乙型肝炎患者中性粒细胞趋化功能与脂质过氧化的关系。方法应用琼脂糖淀胶玻片法和化学比色法对102例慢性乙型肝炎患者进行中性粒细胞趋化功能测定和超氧化物歧化酶(SOD)、丙二醛(MDA)水平检测,并与35例健康人作比较。结果各型慢性乙型肝炎患者趋化指数和SOD水平均低于健康对照组(P<0.01),而MDA水平高于健康对照组(P<0.01),血清SOD水平与MDA水平呈显著负相关(r=-0.468 4,P<0.01),结论慢性乙型肝炎患者中性粒细胞趋化功能的降低与脂质过氧化有一定的相关性。
Objective To explore the relationship of detection of neutrophilic chemotactic function and serum lipid peroxidation injury in patients with chronic hepatitis B.Methods Neutrophilic chemotactic function,serum SOD,MDA（with chemistry） levels were detected in 102 cases with chronic hepatitis B and 35 controls.Results Neutrophilic chemotactic indexes and sercm SOD levels were significantly lower than those in controls（P0.01）,but serum MDA levels were significantly higher than controls（P0.01）,serum SOD levels were negatively correlated with MDA levels（r=-0.468 4）.Conclusion The neutrophilic chemotactic function decreasing in patients with chronic hepatitis B can be closely related to lipid peroxidation injury.
出处
《检验医学与临床》
CAS
2013年第1期60-60,62,共2页
Laboratory Medicine and Clinic
