依达拉奉治疗急性脑出血的临床疗效观察

Clinical efficacy of edaravoneon maleate in treatment of acute cerebral hemorrhage

目的观察依达拉奉治疗急性脑出血的临床疗效。方法将80例急性脑出血患者随机分为治疗组和对照组,每组40例,对照组给予常规治疗,治疗组在常规治疗基础上加用依达拉奉静脉滴注,连用14d。两组均在治疗前及治疗14d后进行神经功能缺损评分及临床疗效评定。结果依达拉奉组治疗14d后神经功能缺损有明显改善;依达拉奉组总有效率明显高于对照组总有效率,差异有统计学意义(P<0.05)。结论依达拉奉治疗急性脑出血安全有效,值得临床推广应用。

Objective To observe the efficacy of edaravoneon maleate in the treatment of acute cerebral hemorrhage. Methods Eighty patients with acute cerebral hemorrhage were randomly divided into two groups, including treatment group （n = 40） and control group （n = 40）, control group were given conventional theray, and treatment group were edaravoneon and conventional treatment for 14 days. Before and after 14 days, the patients in two groups were recorded on neurological function feficit scores, efficacy assessment. Results The edaravoneon group neurologic deficits had very clear improvement after 14 days. The total effective rate of the edaravoneon group was significantly higher than that of the control group. There were statistical differences between two groups （P 0.05）. Conclusion Edaravone is an effective and safe method in treating patients with acute cerebral hemorrhage, which should be worth being widely promoted in clinic.