奥美拉唑联合铝碳酸镁治疗胃溃疡合并胃出血效果观察

Effect observation on omeprazole and hydrotalcite in the treatment of gastric ulcer with the complication of gastrorrhagia

目的探讨奥美拉唑联合铝碳酸镁治疗胃溃疡合并胃出血的治疗效果。方法选取2011年3月～2012年3月入住本院并接受治疗的胃溃疡合并胃出血患者132例,将所有患者随机分为观察组和对照组,每组患者66例,对照组采用传统治疗方案,观察组采用奥美拉唑联合铝碳酸镁治疗方案。结果观察组治愈41例,治愈率为62.1%,总有效率为97.0%;对照组治愈28例,治愈率为42.4%,总有效率为89.4%。观察组胃出血复发率仅为9.1%,低于对照组的31.8%。观察组患者满意度为98.5%,高于对照组的92.4%。结论奥美拉唑联合铝碳酸镁应用于胃溃疡合并出血患者治疗效果显著,值得临床推广应用。

Objective To explore the curative effect of omeprazole and hydrotalcite in the treatment of gastric ulcer with the complication of gastrorrhagia. Methods One hundred and thirty-two patients suffering from gastric ulcer accompanying with gastrorrhagia from March 2011 to March 2012 admitted into our hospital were randomly divided into two groups： observation group （n = 66） and control group （n = 66）. In control group, conventional treatments were provided; while in observation group, patients were treated by omeprazole and hydrotalcite. Results In observation group, 41 patients were cured accounting for 62.1%, the total curative effect rate was 97.0%; in control group, 28 patients were cured accounting for 42.4%, the total curative effect rate was 89.4%. The recurrent rate of gastrorrhagia in observation group was only 9.1%, which was lower than 31.8% of the control group. The patient satisfaction in observation group reached up to 98.5%, which was higher than 92.4% of the control group. Conclusion Combining application of omeprazole and hydrotalcite to treat gastric ulcer with the complication of gastrorrhagia obtains a remarkable curative effect, which is worthy of extension in clinic.