低浓度舒芬太尼联合曲马多在老年患者术后静脉镇痛的疗效观察

Effect observation of low concentrations of Sufentanil combined Tramadol in postoperative intravenous analgesia for elderly patients

目的观察低浓度舒芬太尼复合曲马多在老年患者术后静脉镇痛中的疗效。方法将本院2011年6月～2012年6月92例外科老年患者随机分为两组,观察组46例患者术后采用舒芬太尼复合曲马多静脉镇痛,对照组46例患者采用舒芬太尼静脉镇痛,采用VAS评分对术后4、12、24、48h疼痛情况进行比较,并对不良反应进行观察。结果观察组各时间段疼痛评分略低于对照组,但两组于术后12h后评分均在3分以下,组间比较差异无统计学意义(P>0.05)。观察组不良反应发生率为6.52%;对照组不良反应发生率为32.61%;观察组不良反应发生率明显低于对照组,两组比较,差异有统计学意义(P<0.05)。结论低浓度舒芬太尼复合曲马多静脉镇痛在确保镇痛效果的同时,可减少阿片类药物的用量,从而降低不良反应发生率,适合老年患者术后镇痛。

Objective To investigate the clinical effect of low concentrations of Sufentanil combined Tramadol in postoperative intravenous analgesia for elderly patients. Methods Ninety-two cases of elderly patients in surgical were randomly divided into two groups in our hospital from June 2011 to June 2012, 46 cases of the observation group were given Sufentanil combined Tramadol in postoperative intravenous analgesia, 46 cases of the control group were given Shufentanyl in postoperative intravenous analgesia, then compared the visual analog pain score （VAS） of two groups after 4, 12, 24, 48 h, and observed the adverse reactions. Results The pain score of observation group at each time was slightly lower than the control group, but the scores of two groups in postoperative 12 h were all at 3 points or less, the difference between the two groups were not statistically significant （P 0.05）. The incidence of adverse reactions of observation group was 6.52%, and the control group was 32.61%; the incidence of adverse reactions of observation group was significantly lower than the control group, the difference was statistically significant （P 0.05）. Conclusion Low concentrations of Sufentanil combined Tramadol in intravenous analgesia can ensure the analgesic effect, and reduce the amount of opiate drug, reduce the incidence of adverse reactions, it is suitable for elderly patients with postoperative analgesia.