欣母沛治疗子宫收缩乏力性产后出血的临床分析

Analysis on the Clinical Hemabate in Treatment of Uterine Contraction Asthenia Postpartum Hemorrhage

目的:探讨欣母沛在治疗子宫收缩乏力性产后出血的临床疗效。方法:选择2011年12月-2012年6月在笔者所在医院收治的产后出血产妇共96例,随机分为缩宫素组(先宫底注射缩宫素20U,再采用5%葡萄糖液500ml加缩宫素20U静脉滴注治疗)与欣母沛组(注射、静滴缩宫素并联合应用欣母沛治疗)各48例,观察两组产妇产后2h与24h出血量、子宫收缩情况及用药后的不良反应。结果:欣母沛组产后2h与24h出血量分别为(191.43±56.53)ml、(296.69±55.91)ml,与缩宫素组(323.65±68.77)ml、(402.82±67.88)ml比较差异有统计学意义(P<0.05);欣母沛组子宫收缩总有效率为93.75%,与缩宫素组子宫收缩总有效率81.25%比较差异有统计学意义(P<0.05)。两组产妇在用药后不反应分别为6.3%和8.3%,比较差异无统计学意义(P>0.05)。结论:欣母沛在治疗缩乏力性产后出血有显著的疗效,是简单、安全的有效方法,值得临床广泛使用.

Objective：To investigate the hemabate in treatment of uterine contraction asthenia postpartum hemorrhage.Method：From 2011 December to 2012 June,choose 96 cases of postpartum hemorrhage in our hospital,randomized to oxytocin group（using a 5% glucose solution 500 ml and oxytocin 20 U intravenously） with hemabate group（intravenous drip of oxytocin and combined application of hemabate on） 48 cases were observed in the two groups,2 h and 24 h in maternal postpartum bleeding,uterine contraction and after drug adverse reaction.Result：Hemabate group of postpartum 2 h and 24 h output respectively（191.43±56.53） ml,（296.69±55.91） ml,and oxytocin group（323.65±68.77） ml,（402.82±67.88） ml compared the difference was statistically significant（P0.05）;uterine contraction of hemabate group total rate of 93.75% and oxytocin group contraction of the uterus the total efficiency of 81.25%,compared the difference was statistically significant（P0.05）.Two groups of women after treatment response were 6.3% and 8.3%：the differences were not statistically significant（P0.05）.Conclusion：Hemabate in treatment of postpartum hemorrhage of uterine atony shrinkage has significant curative effect,is simple,safe and effective method,is worth the clinical widely used.