紫杉醇和三尖杉磷碱色谱过程的模型研究(Ⅱ)

Study on the Model Used in the Chromatography Process of Taxol and Cephalmonnine(Ⅱ)

根据建立的液相色谱普遍化速率模型 ,模拟了比渥数、η数、传质彼克列数、粒径、进样量和溶质分子直径同多孔粒子孔径比对紫杉醇色谱峰峰形和紫杉醇和三尖杉磷碱色谱分离度的影响 ,获得了控制紫杉醇和三尖杉磷碱色谱过程的主要影响因素 ,从而为紫杉醇和三尖杉磷碱的色谱分离提供了更好的理论指导。

On the basis of the general chromatography rate model,the effects of Bi number, η number,mass transfer Pe L number,particle diameter,injection and ratio of solute diameter and pore diameter on the chromatographic peak of taxol and the separation of taxol and cephalmonnine were simulated with computer.The essential factors affect on the chromatographic process of taxol and cephalmonnine were obtained and a more useful theory was provided to direct the chromatography separation of taxol and cephalmonnine.