微生物代谢合成法在莽草酸及其衍生物研究中的应用

The application of microbial metabolic synthesis in shikimic acid and its derivatives

天然产物莽草酸(Shikimic acid)具有抗肿瘤、抗血栓等药理活性,在生物及化学合成中扮演着重要角色,而倍受关注。本文综述了近年来国内外有关微生物代谢合成法在莽草酸及其衍生物研究中的应用,为莽草酸的开发利用提供参考。

The major pharmacological activities of Shikimic acid include antitumor,antithrombotic etc.Shikimic acid plays an important role in the biological and chemical synthesis,so it has attracted the attention of the scholar.To provide the references on development and utilization of Shikimic acid.In this paper,the research on the application of microbial metabolic synthesis in shikimic acid and its derivatives was reviewed in recent years.