我院2009-2011年抗凝、抗血小板药应用分析

Analysis of the Utilization of Anticoagulant or Antiplatelet Drugs in Our Hospital from 2009 to 2011

目的:评价我院抗凝、抗血小板药的应用情况及趋势。方法:对我院2009-2011年抗凝、抗血小板药的总销售金额、用药频度(DDDs)、日均费用(DDC)等进行统计、分析。结果:我院抗凝、抗血小板药的总销售金额呈逐年下降趋势;销售金额排序列前10位的药品以具有抗凝、抗血小板作用的中成药制剂为主,其DDDs呈下降趋势,部分药品的DDC较高(均>100元),药品费用与DDDs同步性较差;临床一线用药中,以阿司匹林、氯吡格雷为主,其各年度的销售金额、DDDs均逐年增加,患者选择应用的倾向性较大,药品费用与DDDs同步性较好。结论:我院具有抗凝、抗血小板作用的药品在临床应用广泛,有逐年减少的趋势。但仍需注重用药的安全、合理、经济,以提高药品疗效和减少不良事件的发生。

OBJECTIVE： To evaluate the utilization and trend of anticoagulants and antiplatelet drugs in our hospital. METHODS： The utilization of anticoagulants and antiplatelet drugs in our hospital during 2009--2011 was analyzed statistically in terms of consump- tion sum, DDDs, DDC, etc. RESULTS： The consumption sum of anticoagulants and antiplatelet drugs dropped year after year. Top 10 drugs in the list of consumption sum mainly were Chinese patent medicine preparation with anticoagulant and antiplatelet effect, DDDs of which was decreasing, while DDC of part of drugs was high comparatively （〉100 yuan）. The synchronization of drug cost and DDDS was poor. Among first-line drugs, mainly including aspirin and clopidogrel, the consumption sum and DDDs of them increased year after year, as the first choice in the clinic; the cost of other ones was better in the synchronization of DDDs. CONCLUSION： An- ticoagulants and antiplatelet drugs are widely used in our hospital, decreasing year by year. But we should pay attention to the safe, rea- sonable and economical use of drugs to improve therapeutic efficacy and reduce the occurrence of adverse events.