摘要
目的:了解我院药品不良反应(ADR)的发生情况,以便更好地为临床用药提供切实的依据,保证用药的安全合理。方法:回顾性分析并统计我院2009年1月-2012年5月临床上报的1419例报告。结果:1419例ADR报告中,男性患者601例,女性患者818例;静脉滴注引发ADR822例,占51.15%;发生ADR的人群主要以中老年患者为主。抗微生物药引起的ADR报告中,头孢菌素类抗微生物药引发例数最多,共计239例;皮肤及其附件损害所占比例最高(占38.63%)。结论:临床用药中,应注意ADR对皮肤的影响,及对抗微生物药做过敏性试验,确保用药安全、有效。
OBJECTIVE: To investigate the occurrence of ADR in our hospital, and to provide reference for clinical drug use and guarantee the safety of drug use. METHODS: During Jan. 2009--May 2012, 1 419 ADR cases reported in our hospital were analyzed retrospectively. RESULTS: Of 1 419 ADR reports, there were 601 male patients and 818 female patients. 822 cases were cause by intravenous dripping, accounting for 51.15%. ADR cases mostly occurred in middle-age and elderly group. Among ADR cases induced by antibiotics, a large number of cases were caused by cephalosporin antibiotics, involving 239 cases. Skin injury took up the highest proportion (38.63 % ). CONCLUSION: Great importance should be attached to the effect of ADR on gastrointes- tinal tract and sensitivity test of antibiotics to guarantee the safety and effectiveness.
出处
《中国药房》
CAS
CSCD
2013年第6期541-542,共2页
China Pharmacy